Grant holder information


We expect all NC3Rs-funded researchers to act as 3Rs ambassadors within their institutions and field, promoting the 3Rs outcomes of the research we support in publications, posters and presentations. In addition, grant holders are required to:

Grant extensions | Publications and open access | Reporting requirements and evaluation

Grant extensions

The NC3Rs does not routinely extend awards, except for maternity leave, gaps in employment or staggered start dates. Extensions for these reasons may be requested through a direct request to a member of the NC3Rs funding team.

In exceptional circumstances, we may consider extending the grant. The delays or shortfall must seriously threaten the delivery of a significant proportion of the science outlined in the original application. Applicants must be able to demonstrate that the delays could not have been anticipated, were outside their control and that every effort has already been made to mitigate them.

Extensions cannot be used for:

  • The sole purpose of using remaining funds
  • Starting new scientific work that was not outlined in the original application
  • Managing RO or applicant changes to research plans and staffing
  • Preparing new grant applications (including fellowship applications)
  • The purpose of writing up results

With the exception of multiple periods of maternity/paternity/sick leave, a grant will be allowed no more than one extension. If an extension has already been approved, further requests will not normally be considered. 

Requests for additional funds will only be considered in exceptional circumstances. 

Publications and open access publishing

We have adopted the RCUK’s policy on open access of publications. We expect NC3Rs grant holders to disseminate their results by publishing in appropriate scientific journals, detailing the 3Rs impact of the work. The NC3Rs contribution to Article Processing Charges (APCs) will be paid for via the MRC contribution to the RCUK block grant.

Peer reviewed papers reporting research that is wholly or partially funded by the NC3Rs should:

  • Make reference to the 3Rs implications of the research, including in the abstract and the main body of the text.
  • Be published in journals which are compliant with the RCUK policy on open access.
  • Include details of the funding that supported the research - NC3Rs support for an individual or research project should be acknowledged in all publications where such support has been significant (i.e. accounts for at least 20% of funding).
  • Provide a statement on how the underlying research materials such as data, samples or models can be accessed.
  • Be reported in accordance with the ARRIVE guidelines, taking into account the specific editorial policies of the journal concerned.

Guidance text for acknowledging the NC3Rs:

'We thank the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for funding this work ([insert grant number] to [insert author(s) initials]). Article processing charges were paid from the Medical Research Council contribution to the RCUK block grant to [insert name of institution].'

Please keep us informed of any publications or other material arising from an NC3Rs award by emailing a PDF copy to  Ideally, we would like to be informed pre-publication to enable us to prepare publicity material as appropriate. Any publication arising from NC3Rs-funded research should be deposited into Europe PubMed Central at the point of publication or within six months at the latest and included in your Researchfish grant record.

NC3Rs blog: NC3Rs-funded research now available for all

Reporting requirements and evaluation

Grant holders should report on the outputs and outcomes of the research we have funded on a regular basis. In line with the Research Councils, we use Researchfish to collect this information. Log-in details are provided by Researchfish Ltd. Outputs and outcomes data should be submitted during and after the lifetime of the award. Data can be inputted at any time. In addition, there is an annual compulsory data submission period. Information in Researchfish should also be updated shortly before the grant is due to end. Failure to update within three months of the grant end date will result in an automatic financial penalty.

We reserve the right to sanction a grant at any stage if unsatisfactory progress has been made.


  • Compliance with Researchfish reporting is a requirement for every grant awarded by the NC3Rs (including CRACK IT awards).
  • The Principal Investigator is ultimately responsible for ensuring his/her Researchfish record is maintained.


  • Grant holders should enter information into Researchfish all year round and for at least five years after the grant has ended.
  • We also have a mandatory annual collection period when you are required to formally submit your data. For 2019, this will be from 4 February 2019 to 14 March 2019, 4pm.
  • There is also a requirement to update Researchfish when your grant is coming to an end.


  • Details of all outputs, outcomes and impacts, when available, arising from the grant.
  • In particular, complete the sections on Publications and the 3Rs.
  • We have published an Evaluation Framework for assessing 3Rs impact. The framework provides examples of the types of metrics that grant holders should report in Researchfish.


  • Researchfish is one method by which we monitor progress on grants. Researchers who do not report into Researchfish when requested to do so, or use the system inappropriately, will be subject to sanctions (this includes withholding or recovery of grant payments) and will become ineligible to apply for additional grants from the NC3Rs (and potentially the Research Councils). A flag will be applied to the Je-S system so that all Research Councils are aware of the failure to report.
  • Researchfish is not a publicly accessible data repository. However, data held in Researchfish may be used to populate the NC3Rs website and for production of corporate publications such as annual reports.
  • We use information on outputs and impacts in our corporate publications, in case studies, to answer parliamentary questions and to support funding bids for investment in the NC3Rs. A summary of outputs and impacts as reported by our grant holders in the 2018 researchfish® submission period can be accessed here. Please note clicking this link will download a pdf file.

Queries about our reporting requirements should be sent to

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