We expect all NC3Rs-funded researchers to act as 3Rs ambassadors within their institutions and field, promoting the 3Rs outcomes of the research we support in publications, posters and presentations. In addition, grant holders are required to:
- Implement the principles in the cross-funder guidance Responsibility in the Use of Animals in Bioscience Research.
- Where non-human primates are used, implement the principles in the NC3Rs guidelines Primate Accommodation, Care and Use.
- Abide by the UKSBS/NC3Rs policy on preferred suppliers of antibodies.
- Abide by UKRI Terms and Conditions and additionally to the NC3Rs Terms and Conditions. Any additional NC3Rs conditions will be included in the award letter.
- Joint CRUK-NC3Rs award holders of skills and knowledge transfer grants will need to abide by additional joint terms and conditions.
- Training Fellowship award holders are required to abide by Fellowship Terms and Conditions.
- Studentship award holders should abide by the Terms and Conditions of Research Council Training Grants, and where applicable, the BHF/NC3Rs joint award terms and conditions.
The NC3Rs does not routinely extend awards, except for maternity leave, gaps in employment or staggered start dates. Extensions for these reasons may be requested through a direct request to a member of the NC3Rs funding team.
In exceptional circumstances, we may consider extending the grant. The delays or shortfall must seriously threaten the delivery of a significant proportion of the science outlined in the original application. Applicants must be able to demonstrate that the delays could not have been anticipated, were outside their control and that every effort has already been made to mitigate them.
Extensions cannot be used for:
- The sole purpose of using remaining funds
- Starting new scientific work that was not outlined in the original application
- Managing RO or applicant changes to research plans and staffing
- Preparing new grant applications (including fellowship applications)
- The purpose of writing up results
With the exception of multiple periods of maternity/paternity/sick leave, a grant will be allowed no more than one extension. If an extension has already been approved, further requests will not normally be considered.
Requests for additional funds will only be considered in exceptional circumstances.
We have adopted the RCUK’s policy on open access of publications. We expect NC3Rs grant holders to disseminate their results by publishing in appropriate scientific journals, detailing the 3Rs impact of the work. The NC3Rs contribution to Article Processing Charges (APCs) will be paid for via the MRC contribution to the RCUK block grant.
Peer reviewed papers reporting research that is wholly or partially funded by the NC3Rs should:
- Make reference to the 3Rs implications of the research, including in the abstract and the main body of the text.
- Be published in journals which are compliant with the RCUK policy on open access.
- Include details of the funding that supported the research - NC3Rs support for an individual or research project should be acknowledged in all publications where such support has been significant (i.e. accounts for at least 20% of funding).
- Provide a statement on how the underlying research materials such as data, samples or models can be accessed.
- Be reported in accordance with the ARRIVE guidelines, taking into account the specific editorial policies of the journal concerned.
Guidance text for acknowledging the NC3Rs:
'We thank the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for funding this work ([insert grant number] to [insert author(s) initials]). Article processing charges were paid from the Medical Research Council contribution to the RCUK block grant to [insert name of institution].'
Please keep us informed of any publications or other material arising from an NC3Rs award by emailing a PDF copy to email@example.com. Ideally, we would like to be informed pre-publication to enable us to prepare publicity material as appropriate. Any publication arising from NC3Rs-funded research should be deposited into Europe PubMed Central at the point of publication or within six months at the latest and included in your Researchfish grant record.
NC3Rs blog: NC3Rs-funded research now available for all
Grant holders should report on the outputs and outcomes of the research we have funded on a regular basis. In line with the Research Councils, we use Researchfish to collect this information. Log-in details are provided by Researchfish Ltd. Outputs and outcomes data should be submitted during and after the lifetime of the award. Data can be inputted at any time. In addition, there is an annual compulsory data submission period. Information in Researchfish should also be updated shortly before the grant is due to end. Failure to update within three months of the grant end date will result in an automatic financial penalty.
We reserve the right to sanction a grant at any stage if unsatisfactory progress has been made.
Queries about our reporting requirements should be sent to 3Rsgrants@nc3rs.org.uk