£50M in replacement technologies
We have recently reached the important milestone of awarding over £50M to research to replace the use of animals.
We have funded the development of a range of complex in vitro and in silico models as well as supported the use of partial replacements through the use of so-called non-protected species such as the fruit fly, which based on current scientific thinking are not considered capable of suffering.
Read on to learn more about the outcomes and impacts arising from NC3Rs-funded replacement technologies including case studies from our grant holder's research.
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Case studies
Dr Elizabeth Ballou was awarded funding to validate an in vitro titanisation assay for Cryptococcus neoformans to build confidence in its utility to replace animal studies.
Growth and development of parasite worms in vitro
Professor Aaron Maule was awarded funding to further develop a culture method for liver fluke replacing the need to grow and develop the parasites rodents.
The lung's first line of defence
Dr Gyorgy Fejer was awarded funding to transfer skills and protocols to establish alveolar macrophage cell lines replacing the need to isolate cells from mouse organs or bone marrow.
Wax moths and tuberculosis research
Professor Paul Langford was awarded funding to develop a tuberculosis infection model using Galleria mellonella to replace the use of mammals in some studies.
For more information
Learn more about our funded awards focusing on replacing animals in research on our portfolio pages.