Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration Principal Investigator: Dr Tomas Bellamy, University of Nottingham PhD Studentship
A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research Principal Investigator: Professor Cathy Merry, University of Nottingham Project grant
Development and characterisation of a human ex vivo model of aneurysm Principal Investigator: Dr Jason Johnson, University of Bristol PhD Studentship
Probing in vivo parasite biology in vitro Principal Investigator: Professor Aaron Maule, Queen's University Belfast Project grant
Modelling liver fibrosis using human Induced Pluripotent Stem Cells Principal Investigator: Dr Ludovic Vallier, University of Cambridge Project grant
An organotypic model of bronchial dysplasia Principal Investigator: Dr Frank McCaughan, University of Cambridge PhD Studentship
C. elegans model to unravel the role of Klotho in ion metabolism and ageing Principal Investigator: Dr Tarja Kinnunen, University of Huddersfield PhD Studentship
Enhancing mouse whole embryo culture for use in birth defects research Principal Investigator: Professor Andrew Copp, University College London PhD Studentship
Human stem cell derived neurones and astrocytes as an in vitro model of human prion infection and replication Principal Investigator: Professor Siddharthan Chandran, University of Edinburgh Project grant
Development of a tetanus-sensitive cell line for assaying tetanus toxin activity Principal Investigator: Professor Bazbek Davletov, University of Sheffield Project grant
A non-mammalian model for neurofunctional studies of vertebrate dopamine signalling Principal Investigator: Dr Jonathan McDearmid, University of Leicester PhD Studentship
An ovarian cancer model on a chip Principal Investigator: Dr Julien Gautrot, Queen Mary University of London PhD Studentship
DictyMyc: Using Dictyostelium to study the genetic basis of Mycobacterium bovis intracellular infection Principal Investigator: Professor Graham Stewart, University of Surrey Strategic grant
Replacing, reducing and refining the use of animals in anti-filarial drug testing Principal Investigator: Dr Joseph Turner, Liverpool School of Tropical Medicine PhD Studentship
Developing and validating an in vitro mycobacterial challenge model to facilitate TB vaccine research and minimise in vivo challenge Principal Investigator: Professor Helen McShane, University of Oxford Strategic grant
Development of an in vitro model of 'pain' Principal Investigator: Dr Ramin Raouf, King's College London Project grant
A non-mammalian model to study innate immune modulation of airways remodelling in asthma Principal Investigator: Professor Stephen Renshaw, University of Sheffield Strategic grant
Use of Drosophila models to explore the function of asthma susceptibility genes Principal Investigator: Professor Donna Davies, University of Southampton Strategic grant
Developing a model for the study of respiratory inflammation in the zebrafish Principal Investigator: Professor Margaret Dallman, Imperial College London Strategic grant
Novel biomarker platform for a 3Rs approach to assessment of developmental and reproductive toxicity Principal Investigator: Dr Catherine Pears, University of Oxford Project grant