In silico design and optimisation of novel host-directed therapies Principal Investigator: Dr Reiko Tanaka, Imperial College London PhD Studentship
Organoid and single cell models of bladder cancer Principal Investigator: Professor Margaret Knowles, University of Leeds PhD Studentship
In vitro reconstitution of the polymicrobial community associated with cystic fibrosis airway infections Principal Investigator: Dr Martin Welch, University of Cambridge PhD Studentship
Replacing liver cancer models by modeling human liver cancer in vitro Principal Investigator: Dr Meritxell Huch, University of Cambridge Project grant
Reducing the animal cost of CRISPR/Cas9 mutagenesis Principal Investigator: Dr Ben Davies, University of Oxford Project grant
Development of a biologically-relevant preclinical radiotherapy dosimetry phantom Principal Investigator: Professor Karen Kirkby, University of Manchester PhD Studentship
Investigation of key inflammatory cells & mediators in zebrafish larval tailfin & heart repair/regeneration following resolution of inflammation Principal Investigator: Professor Adriano Rossi, University of Edinburgh PhD Studentship
Developing a novel experimental design and analysis model for longitudinal animal studies with high-dimensional outcomes Principal Investigator: Professor Peter Diggle, Lancaster University PhD Studentship
Dissemination of refinements in mouse experimental stroke models to the scientific community Principal Investigator: Dr Claire Gibson, University of Leicester Skills and Knowledge Transfer grant
Development of an AOP for cardiotoxicity mediated by the blockade of L-type calcium channel Principal Investigator: Dr Luigi Margiotta-Casaluci, Brunel University Strategic grant
High-throughput in vitro culture system for Cryptosporidium oocysts: replacing animals in research Principal Investigator: Professor Joanne Cable, Cardiff University Skills and Knowledge Transfer grant
Modelling central and peripheral nervous system connectivity using compartmentalised microfluidic systems Principal Investigator: Dr Federico Dajas-Bailador, University of Nottingham PhD Studentship
Genetic screens in intestinal/colon organoid (mini-gut) culture using the CRISPR-Cas9 system Principal Investigator: Dr Abdolrahman Shams Nateri, University of Nottingham PhD Studentship
Transfer of a non-human primate (NHP) in vitro functional assay for the early evaluation of TB vaccine candidates and the associated immune response Principal Investigator: Dr Rachel Tanner, University of Oxford Skills and Knowledge Transfer grant
Interrogating the mouse visual system by automated analysis of voluntary behaviour Principal Investigator: Dr Riccardo Storchi, University of Manchester Fellowship
The establishment of left-right asymmetry in mammalian development Principal Investigator: Dr David Turner, University of Liverpool Fellowship
Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts Principal Investigator: Dr Anna Grabowska, University of Nottingham PhD Studentship
Training in hIPSC differentiation protocols to generate motor neuron-muscle cultures to replace rat models in study of mitochondria on axon physiology Principal Investigator: Dr Mark Rigby, King's College London Fellowship
A 3D in vitro glioblastoma cell culture system for identification and evaluation of novel radiosensitisers reducing rodent xenograft studies Principal Investigator: Professor Anthony Chalmers, University of Glasgow Project grant
Development of new experimental models to understand the genetic basis of allergic bronchopulmonary aspergillosis Principal Investigator: Dr Sara Gago, University of Manchester Fellowship