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Activity type

Topic

Model

Impact stories

21 results

Accelerate adoption of engineered vascular tissues with induced pluripotent stem cell-derived smooth muscle cells

Principal Investigator: Professor Manuel Mayr, Imperial College London

Partnerships and impact awards

A collection of test tubes containing coloured liquid

Re: Modification and validation of a human endothelialised in-vitro thrombosis model to promote end-user uptake

Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University

Partnerships and impact awards

Development of a minimally-invasive ultrasound guided rat myocardial infarction model to replace the gold standard invasive thoracotomy approach

Principal Investigator: Dr Mark MacAskill, University of Edinburgh

PhD Studentship

Using a novel human 3D spheroid model to study mechanisms and therapeutics for vascular calcification

Principal Investigator: Professor Cathy Shanahan, King's College London

PhD Studentship

Development and disease modelling in engineered vascular tissues

Principal Investigator: Professor Manuel Mayr, Imperial College London

PhD Studentship

Identification of the molecular and cellular mechanisms driving cardiac fibrosis: A novel ex vivo approach to target identification and validation

Principal Investigator: Dr Lee Borthwick, Newcastle University

PhD Studentship

High fidelity computational approaches to exploit new structures of cardiac ion channels

Principal Investigator: Dr Andrew Leach, University of Manchester

PhD Studentship

Drosophila based screening to replace mammalian systems to identify the functional role of candidate genes in controlling muscle dyadic architecture

Principal Investigator: Professor Andrew Trafford, University of Manchester

PhD Studentship

Modelling of thrombus dynamics in a microfluidic 'vasculature'

Principal Investigator: Dr Nicola Mutch, University of Aberdeen

PhD Studentship

Portrait of Dr Whyte and Professor Mutch

Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity

Principal Investigator: Dr Grant Wheeler, University of East Anglia

PhD Studentship

Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias

Principal Investigator: Dr Katja Gehmlich, University of Birmingham

PhD Studentship

Two headshots side by side. On the left is Max, on the right is Dr Katja Gehmlich

Development and characterization of a novel endothelialized in vitro model of human atherothrombosis

Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University

PhD Studentship

Fusogenic liposomes: the innovative delivery of compounds into human platelets to reduce animal use in platelet research

Principal Investigator: Dr Alice Pollitt, University of Reading

PhD Studentship

Advanced in vitro and in silico models to predict and prevent deep venous thrombosis

Principal Investigator: Dr Alessio Alexiadis, University of Birmingham

PhD Studentship

Using zebrafish embryos to identify genes that protect against atherosclerosis

Principal Investigator: Professor Paul Evans, University of Sheffield

PhD Studentship

Recreating thrombosis models using tissue-engineered arterial constructs: A novel method to reduce and replace mice used in platelet research

Principal Investigator: Dr Alan Harper, Keele University

PhD Studentship

Development of E-Sense: a flexible in vitro platform to determine cardiovascular risk

Principal Investigator: Dr Stephen White, Manchester Metropolitan University

PhD Studentship

Investigation of key inflammatory cells & mediators in zebrafish larval tailfin & heart repair/regeneration following resolution of inflammation

Principal Investigator: Professor Adriano Rossi, University of Edinburgh

PhD Studentship

Reducing animal use in thrombosis research with an ex vivo injury model

Principal Investigator: Dr Matthew Harper, University of Cambridge

PhD Studentship

Developing a Drosophila melanogaster model of the cardiac myocyte action potential to investigate function and performance

Principal Investigator: Dr Jeremy Niven, University of Sussex

PhD Studentship