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Activity type

Topic

Model

Impact stories

16 results

DAR3T: Data Analysis of 3Rs Tools

Principal Investigator: Professor Crispin Miller, University of Glasgow

Strategic grant

Replacing Mouse Immunotherapy Models with Human Colorectal Cancer Organoid - T Cell Cultures

Principal Investigator: Professor Awen Gallimore, Cardiff University

PhD Studentship

Cell culture plate being removed from an incubator

Manipulating cholangiocarcinoma immune-phenotype in a patient derived precision-cut tumour model to improve immune checkpoint inhibition response

Principal Investigator: Dr Laura Randle, University of Liverpool

PhD Studentship

Preclinical Radiomics: A novel approach linking imaging with biological outcomes in mouse models

Principal Investigator: Dr Kathryn Brown, Queen's University Belfast

Fellowship

Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Principal Investigator: Dr Spencer Collis, University of Sheffield

PhD Studentship

Two headshots side by side. On the left is Dr Spencer Collis, on the right is Hannah

A living biobank of post-surgical residual glioblastoma to replace animal studies

Principal Investigator: Dr Spencer Collis, University of Sheffield

PhD Studentship

Refinement of soft tissue targeting and alignment protocols is small animal radiotherapy using an injectable fiducial marker

Principal Investigator: Dr Karl Butterworth, Queen's University Belfast

PhD Studentship

Development of a biologically-relevant preclinical radiotherapy dosimetry phantom

Principal Investigator: Professor Karen Kirkby, University of Manchester

PhD Studentship

An industrial standard cancer drug development platform using human induced pluripotent stem cell technology

Principal Investigator: Dr Deepali Pal, Newcastle University

Fellowship

Towards in vitro oncology trials: drug testing in cultured patient derived tumour organoid cultures

Principal Investigator: Professor Andrew Tutt, King's College London

Project grant

Using chicken eggs to advance the 3Rs in cancer drug discovery

Contractor: Dr Jean Viallet

CRACK IT Solution

Injecting a chicken egg under a spotlight

Developing an Organ on a Chip Model to Test the Therapeutic Efficacy of Adhirons in Breast Cancer

Principal Investigator: Dr Darren Tomlinson, University of Leeds

PhD Studentship

Labelled IMS TAG Proteins for Quantitative Mass Spectrometry Imaging

Principal Investigator: Professor Malcolm Clench, Sheffield Hallam University

Strategic grant

Rows of PCR tubes on a yellow background

Non-invasive imaging to reduce and refine the use of animals and monitor their welfare during the course of experimentations in oncology

Principal Investigator: Dr Francois Lassailly, Cancer Research UK

Pilot study grant

Using the Drosophila fly intestine to investigate Wnt targets in vivo

Principal Investigator: Dr Owen Sansom, University of Glasgow

Project grant

Improving the predictive power of models for cancer research

Current contact: Dr Anthony Holmes

Office-led project

Microscope image of cells glowing purple