Mature human iPSC-derived atrial cardiomyocytes to replace animals in the study of atrial fibrillation Principal Investigator: Dr Patrizia Camelliti, University of Surrey PhD Studentship
Re: Modification and validation of a human endothelialised in-vitro thrombosis model to promote end-user uptake Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University Partnerships and impact awards
Replacement of in vivo arterial thrombosis models using human placental arteries: The birth of a new approach Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University Project grant
Development of 'human stroke-on-a-chip' model to replace rodent stroke models Principal Investigator: Dr Hilary Carswell, University of Strathclyde PhD Studentship
Revolutionising relative bioavailability testing: Using AI-PAT to eliminate animal models Principal Investigator: Professor Hannah Batchelor, University of Strathclyde Strategic grant
Bioreactor infrastructure for organoid culture in human models of reproductive diseases Principal Investigator: Professor Andrew Blanks, University of Warwick Strategic grant
Novel bioprinters for 3D In Vitro Models (3D-IV) Principal Investigator: Professor Kenneth Dalgarno, Newcastle University Strategic grant
Establishing a core infrastructure for enhancing gut health, disease and microbiome research using advanced non-animal models Principal Investigator: Dr Tamás Korcsmáros, Imperial College London Strategic grant
DAR3T: Data Analysis of 3Rs Tools Principal Investigator: Professor Crispin Miller, University of Glasgow Strategic grant
A world-class in vitro models facility for the UK community, reducing the barriers to adoption to drive animal replacement Principal Investigator: Professor Hazel Screen, Queen Mary University of London Strategic grant
Scaling up human pluripotent stem cell delivery and distribution facilitating reduction in animal use Principal Investigator: Professor Kate Storey, University of Dundee Strategic grant
A core facility for human induced pluripotent stem cells for neurological disease Principal Investigator: Professor Selina Wray, University College London Strategic grant
Characterisation of antibodies and affinity reagents to promote the adoption of robust and reproducible non-animal reagents Principal Investigator: Dr Harvinder Virk, University of Leicester Strategic grant
Revolutionizing micro-surgical training by reducing and replacing animal dependency through synthetic biomimetic 3D printed blood vessels Principal Investigator: Professor Deepak Kalaskar, University College London Strategic grant
Validation of non-animal derived products for stem cell-derived breast cancer organoid models Principal Investigator: Dr Cinzia Allegrucci, University of Nottingham Strategic grant
Direct replacement of secondary antibodies by affimer proteins in lateral flow devices Principal Investigator: Dr Christian Tiede, University of Leeds Strategic grant
An animal-free future for heart research: functional characterisation of novel refined human engineered heart tissue Principal Investigator: Professor Helen Maddock, Coventry University Strategic grant
Towards a clinical-trial-in-a-dish: Validating an animal product free stem cell-derived 3D model of Alzheimer’s disease for drug discovery Principal Investigator: Dr Mattéa Finelli, University of Nottingham Strategic grant
Calf-Free Research: Developing robust approaches to replace foetal calf serum with synthetic alternatives in cell culture Principal Investigator: Dr Manuela Natoli, The Francis Crick Institute Strategic grant
Investigating the replacement of non-animal derived antibodies and serum in academic research Principal Investigator: Dr Julia Needham, MRC London Institute of Medical Sciences Strategic grant