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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

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Topic

Model

Impact stories

40 results

Zebrafish models of Major Depressive Disorder as a replacement for rodent models

Principal Investigator: Professor Robert Hindges, King's College London

PhD Studentship

Building confidence in non-protected zebrafish embryo-larvae as a viable alternative to mammalian DART assessment

Principal Investigator: Dr Jonathan Ball, University of Exeter

PhD Studentship

Establishment of the thermotolerant Arabian killifish as a model for infection studies

Principal Investigator: Dr Tetsuhiro Kudoh, University of Exeter

Project grant

Embryonic zebrafish models of HACD1-deficiency to replace mammals in congenital myopathy and lipidomic research

Principal Investigator: Dr Gemma Walmsley, University of Liverpool

PhD Studentship

Modulating Macrophage Phenotypes During Infection In Zebrafish

Principal Investigator: Dr Phillip Elks, University of Sheffield

PhD Studentship

Refinement of pre-exposure programs to reduce the use of fish in proliferative kidney disease monitoring in aquaculture

Principal Investigator: Dr Hanna Hartikainen, University of Nottingham

PhD Studentship

Refining the tagging of wild fish and sharks

Principal Investigator: Dr Matthew Witt, University of Exeter

PhD Studentship

Dr Matthew Witt with two boats on grass in the background

A non-protected larval zebrafish model for the investigation of novel strategies to protect against nerve agent-induced toxicity and seizures

Principal Investigator: Dr Matthew Parker, University of Portsmouth

Skills and Knowledge Transfer grant

A stock image of round glass dishes containing blue and green liquid arranged closely together.

Identifying and addressing challenges in fish vitellogenin assessment

Current contact: Dr Natalie Burden

Office-led project

Understanding brain regeneration in a zebrafish larval model of intracerebral haemorrhage

Principal Investigator: Dr Siobhan Crilly, University of Manchester

Fellowship

A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders

Principal Investigator: Dr Rhiannon Morgan, University of Liverpool

Fellowship

Using zebrafish embryos to identify genes that protect against atherosclerosis

Principal Investigator: Professor Paul Evans, University of Sheffield

PhD Studentship

The role of water chemistry in zebrafish welfare and reproducibility of research studies

Principal Investigator: Professor Roderic Wilson, University of Exeter

Project grant

Identifying regulators of tissue regeneration by in vivo imaging in the zebrafish

Principal Investigator: Dr Robert Knight, King's College London

PhD Studentship

Quantifying the potential of skin swabbing as a refinement for DNA sampling of laboratory fish

Principal Investigator: Dr Will Norton, University of Leicester

Project grant

a zebrafish is held in a hand net and swabbed.

Investigation of key inflammatory cells & mediators in zebrafish larval tailfin & heart repair/regeneration following resolution of inflammation

Principal Investigator: Professor Adriano Rossi, University of Edinburgh

PhD Studentship

Automated predictive welfare assessment in groups of fish

Principal Investigator: Professor Oliver Burman, University of Lincoln

Project grant

Developing a zebrafish model of neurovascular coupling (NVC)

Principal Investigator: Dr Clare Howarth, University of Sheffield

Project grant

Developing alternative models to evaluate the impact of nanomaterials on neutrophils during the stimulation and resolution of inflammation

Principal Investigator: Dr Helinor Johnston, Heriot-Watt University

Project grant

Refinement of hematopoietic cell transplantation using optical imaging in zebrafish

Principal Investigator: Professor Margaret Dallman, Imperial College London

PhD Studentship