Developing an Organ on a Chip Model to Test the Therapeutic Efficacy of Adhirons in Breast Cancer Principal Investigator: Dr Darren Tomlinson, University of Leeds PhD Studentship
Development of functional 3D human intestinal mucosae to replace rodent models and improve the predictive accuracy of existing in vitro systems Principal Investigator: Professor Stefan Przyborski, Durham University PhD Studentship
Developing a Drosophila melanogaster model of the cardiac myocyte action potential to investigate function and performance Principal Investigator: Dr Jeremy Niven, University of Sussex PhD Studentship
Developing Human Glioma OrganDot Cultures Principal Investigator: Professor William Gray, Cardiff University PhD Studentship
Refining an in vitro system of predictive biomarkers of in vivo liposome efficacy Principal Investigator: Dr Andrew Devitt, Aston University PhD Studentship
Using zebrafish for pre-clinical brain haemorrhage research Principal Investigator: Professor Stuart Allan, University of Manchester PhD Studentship
Building brains in a dish - using ES cells to understand brain development Principal Investigator: Dr John Mason, University of Edinburgh PhD Studentship
In silico human-based methodologies for evaluation of drug cardiac safety and efficacy Principal Investigator: Professor Blanca Rodriguez, University of Oxford Infrastructure grant
Metaboderm: 3D hiPSC derived skin model and in-silico skin modelling of metabolism Contractor: Newcells Biotech Ltd, CRACK IT Challenge
InMutaGene: A human IPS cell model for gene therapy vector safety evaluation Contractor: GeneWerk GmbH, CRACK IT Challenge
A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo Principal Investigator: Dr Alessio Vagnoni, Fellowship
Development of a novel cell based bitter taste assessment assay Principal Investigator: Dr Afzal Rahman Mohammed, Aston University PhD Studentship
A bovine alveolus model to replace cattle in the study of host-pathogen interactions in bovine tuberculosis Principal Investigator: Professor Mark Chambers, University of Surrey Strategic grant
Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration Principal Investigator: Dr Tomas Bellamy, University of Nottingham PhD Studentship
A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research Principal Investigator: Professor Cathy Merry, University of Nottingham Project grant
Development and characterisation of a human ex vivo model of aneurysm Principal Investigator: Dr Jason Johnson, University of Bristol PhD Studentship
Portable bioluminescence test for botulinum neurotoxin Contractor: Dr Gregory Stevens, CRACK IT Solution
Probing in vivo parasite biology in vitro Principal Investigator: Professor Aaron Maule, Queen's University Belfast Project grant
Modelling liver fibrosis using human Induced Pluripotent Stem Cells Principal Investigator: Dr Ludovic Vallier, University of Cambridge Project grant