Development of a tetanus-sensitive cell line for assaying tetanus toxin activity Principal Investigator: Professor Bazbek Davletov, University of Sheffield Project grant
A non-mammalian model for neurofunctional studies of vertebrate dopamine signalling Principal Investigator: Dr Jonathan McDearmid, University of Leicester PhD Studentship
An ovarian cancer model on a chip Principal Investigator: Dr Julien Gautrot, Queen Mary University of London PhD Studentship
DictyMyc: Using Dictyostelium to study the genetic basis of Mycobacterium bovis intracellular infection Principal Investigator: Professor Graham Stewart, University of Surrey Strategic grant
Replacing, reducing and refining the use of animals in anti-filarial drug testing Principal Investigator: Dr Joseph Turner, Liverpool School of Tropical Medicine PhD Studentship
Neuratect: microfluidic microtiter plates for in vitro neurotoxicity screening Contractor: Dr Jos Joore, MIMETAS, BV CRACK IT Challenge
Developing and validating an in vitro mycobacterial challenge model to facilitate TB vaccine research and minimise in vivo challenge Principal Investigator: Professor Helen McShane, University of Oxford Strategic grant
ZeGlobalTox: multi-organ toxicity testing in zebrafish Contractor: Dr Davide D'Amico, ZeClinics SL CRACK IT Solution
Development of an in vitro model of 'pain' Principal Investigator: Dr Ramin Raouf, King's College London Project grant
A non-mammalian model to study innate immune modulation of airways remodelling in asthma Principal Investigator: Professor Stephen Renshaw, University of Sheffield Strategic grant
Use of Drosophila models to explore the function of asthma susceptibility genes Principal Investigator: Professor Donna Davies, University of Southampton Strategic grant
Developing a model for the study of respiratory inflammation in the zebrafish Principal Investigator: Professor Margaret Dallman, Imperial College London Strategic grant
Novel biomarker platform for a 3Rs approach to assessment of developmental and reproductive toxicity Principal Investigator: Dr Catherine Pears, University of Oxford Project grant
Developing a non-animal model system to investigate bitter tastants as new treatments for asthma Principal Investigator: Professor Robin Williams, Royal Holloway University of London Strategic grant
The Drosophila adult intestine as a model for radiation tolerance and resistance Principal Investigator: Dr Joaquin de Navascues, Cardiff University Pilot study grant
Inhalation Translation: Differentiating alveolar macrophage responses to inhaled medicines Contractor: Dr Ben Forbes, Kings College London CRACK IT Challenge
Mechanisms of intestinal epithelial responses to inflammatory modulators Principal Investigator: Professor Inke Nathke, University of Dundee Project grant
Development of human ex vivo bone-tumour niche for the study of cancer bone disease Principal Investigator: Dr James Edwards, University of Oxford Pilot study grant
Motor neuron regeneration in larval zebrafish Principal Investigator: Professor Catherina Becker, University of Edinburgh PhD Studentship
Exploitation of an ex vivo disease model to characterise early events in retinal degeneration Principal Investigator: Dr J. Arjuna Ratnayaka, University of Southampton PhD Studentship