The current approach utilises large numbers of mice and non-human primate models and surrogate antibodies that are not the best predictor of human immune system ...
The most representative non-human glaucoma models are primates but there are a number of ethical and economic reasons which make this a difficult model for ...
This proposal aims to develop a novel platform for modelling the different features of NAFLD using human Induced Pluripotent Stem Cells (hIPSCs).
Apr 22, 2016 ... ... non-rodents before they enter first-in-human clinical trials. These studies are usually carried out in species such as dogs, minipigs or non ...
Dec 19, 2025 ... Publication: Reducing non-human primate use in reproductive toxicology. We have co-authored a publication with the Health and Environmental ...
Human tissue and tissue engineering approaches; Using non-mammalian model systems; Applying mathematical modelling. This work is supported by an expert working ...
... non-human primates, which we will publish in 2024. Global harmonisation of testing requirements for pharmaceutical and chemical safety assessment will ...
The safety of new seed lots of the YF vaccine is currently assessed in non-human primates (cynomologus macaques). Animals are innoculated with a test dose ...
Mar 9, 2020 ... ... non-human primate or mini-pig) to assess safety in support of human clinical trials. Moving to one species only would reduce animal use ...
A review published by the Animal Procedures Committee assessing the lifetime experience of non-human primates used in neuroscience research identified skin ...