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Welcome to the new NC3Rs site, find out more about the changes and improvements we have made.

NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

Our funders

The NC3Rs has an annual budget of around £10 million. We receive core funding from the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC), both of which are part of UK Research and Innovation (UKRI).

We also receive funding for specific programmes from the charitable and commercial sectors, and co-funding from other research funders. In 2019/20, this includes the following organisations:

  • Association of the British Pharmaceutical Industry (ABPI)*
  • Arthritis Research UK
  • British Heart Foundation (BHF)
  • Cancer Research UK (CRUK)
  • Engineering and Physical Sciences Research Council (EPSRC)
  • GlaxoSmithKline (GSK)
  • SCJohnson
  • Shell
  • Syngenta
  • The Dow Chemical Company
  • Unilever
  • Wellcome Trust

* in accordance with the ABPI's Code of Practice regulating the pharmaceutical industry, the following companies have provided funding to the NC3Rs as part of the ABPI-NC3Rs collaboration: AstraZeneca, Covance Laboratories, Eli Lily & Company, GlaxoSmithKline, Huntingdon Life Sciences,  Novartis Pharmaceuticals, Pfizer, Shire Pharmaceutical Development, Takeda Cambridge and UCB Pharma.


We have six Regional Programme Managers supporting the application of the 3Rs in Universities and Institutes across England and Wales. These posts are co-funded by the organisations they support, namely:

  • The Francis Crick Institute
  • Great Western 4 Alliance (University of Bath, University of Bristol, Cardiff University and University of Exeter)
  • King’s College London
  • The London School of Hygiene and Tropical Medicine
  • Royal Veterinary College
  • University College London
  • University of Birmingham
  • University of Leicester
  • The University of Liverpool
  • The University of Manchester
  • University of Nottingham
  • University of Oxford
  • The University of Sheffield