Free-to-use interactive tools for research groups and institutions to benchmark their activities and identify new 3Rs opportunities.
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Resources and information about animal-free cell culture media reagents for 3Rs benefits and improved reproducibility.
Resources to support the use of animal-free enzyme technologies and cells.
Resources and case studies about the technologies available to replace animal-derived antibodies.
10 years of CRACK IT webinar: A human stem cell-based in vitro system to assess cardiotoxicity in new drugs.
Hear from the 3Rs Prize winner, Dr Laura Pellegrini (MRC Laboratory of Molecular Biology).
10 years of CRACK IT webinar: The NephroScreen human kidney-on-a-chip platform, which could replace in vivo nephrotoxicity studies in drug development
An introduction to assessing the welfare impact of new enrichment.
The importance of choosing the appropriate type of enrichment, including examples for rodents and zebrafish.
Questions to help you plan your study before it commences.
Using ethograms, preference tests and motivation tests to evaluate enrichment, including example protocols.
Minimising the influence of bias and understanding the limitations of an evaluation.
Using what you have learned to benefit the animals in your care and disseminating your findings.
Frequently asked questions about determining whether your enrichment protocol is appropriate and effective.
Considerations and resources to support in vivo researchers as they return to working with laboratory animals following a lockdown.
In this webinar Professor Paul Flecknell explains the benefits of e-learning for laboratory animal professionals.
A webinar presenting the welfare benefits of playpens for laboratory rats and how to implement them in your facility.
10 years of CRACK IT webinar: The Home Cage Analyser, which provides continuous monitoring of group-housed rodents.
10 years of CRACK IT webinar: an in silico platform developed to model chronic Leishmania infection.
Amanda Novak (Edinburgh) presents advice on good surgical technique and refinements to incorporate into rodent stereotactic surgery procedures.
Practical resources to ensure that the 3Rs are considered and kept a priority when services are disrupted.
Guidelines for establishing, implementing and refining humane endpoints.
Ways to prevent and manage aggression in laboratory animals, with specific advice for a range of mammalian species.
10 years of CRACK IT webinar: A C. elegans platform to assess the developmental and reproductive toxicity (DART) potential of chemicals.