Skip to main content

New funding scheme: £4M available for proposals to establish infrastructure needed to accelerate use of non-animal methods. Apply now.

NC3Rs | 20 Years: Pioneering Better Science

Project grants

Scheme at a glance

A Project grant is a research project which supports the development of new 3Rs approaches and technologies. Applications from any area of medical, biological or veterinary research are within remit – those that integrate a range of disciplines or include an industrial partner are particularly encouraged.

The amount requested should be dependent on the science. Awards are for up to 36 months and funded at 80% of the full economic cost (fEC).

Key dates

Key date Details
19 October 2023 Outline application form available on the new Funding Service (TFS)
16.00, 11 January 2024  Deadline for submitting outline on TFS
March 2024 Outline assessment meeting
Mid-March 2024 Applicants notified of outcome
March 2024 Applicant workshop for those invited to submit full application
16.00, 18 April 2024 Full application deadline on TFS
July 2024 Panel meeting for full applications
Late July 2024 Applicants notified of outcome
September 2024 Grant holder introductory meeting
1 October 2024 Last date for commencing projects

Please sign up to the NC3Rs newsletter for updates on our funding schemes.

Who can apply?

Establishment eligibility

Any UK research establishment including:

  • Higher Education Institutions (HEIs).
  • Independent Research Organisations (IROs).
  • Research Council (RC) Institutes.

Individual eligibility

Applicants should be UK-based researchers who can demonstrate that they:

  • Will direct the proposed research.
  • Will be actively engaged in accomplishing the project’s aims.
  • Hold a graduate degree – the minimum formal qualification required. However, it would normally be expected that an applicant has been awarded a PhD. Applications involving less experienced researchers should be made in collaboration with a more senior colleague.
  • NC3Rs grant holders with more than 12 months remaining on their NC3Rs grant, at the time of application, are not permitted to apply as a Primary Investigator for further NC3Rs funding (excluding CRACK IT, Skills and Knowledge Transfer and Strategic Awards – please contact the Office to discuss).

Overseas researchers

Overseas researchers cannot be Primary Investigators but can be included as collaborators. Overseas co-applicant status can be obtained in exceptional circumstances at the discretion of the NC3Rs – approval must be sought before applying.


The NC3Rs does not allow resubmission of previously unsuccessful proposals, unless explicitly invited by the Panel. 

Proposals previously declined by the NC3Rs will not be considered by another Research Council or funder within 12 months (from the date of submission to the original Research Council) unless substantially revised. More information can be found in the NC3Rs Project grant Applicant guidance.

Please note: The same or similar application cannot be considered by any other Research Council, the Health Departments or any other research funder at the same time

How to apply

We are running this funding opportunity on the new UKRI Funding Service (TFS).

Applicants are advised to read and refer to the NC3Rs Project grants Applicant guidance, which contains more detailed information on submitting both an outline and full application. 

To start an application on the Funding Service use the opportunity reference OPP347: NC3Rs Project grants 2024 Formal outline

Formal outlines and full applications received after 16.00 on the deadline date will not be considered, without exception.

Outline stage

Before submitting a full application applicants are required to submit a formal outline of their research proposal via TFS.

Applicants are strongly encouraged to contact before submitting an outline via TFS to determine whether the proposed research fits the 3Rs remit. Outline applications that do not fit this remit will be rejected at an early stage.

Important points to note at outline stage:

  • No attachments are permitted. All pertinent information must be included in the application form.
  • Applicants are required to provide metrics regarding the potential 3Rs impact of their research as part of their outline proposal, please see Section 3.4.1 of the NC3Rs Project grant Applicant guidance for further information.

Submitting a full application

Successful outline applicants are invited to submit a full proposal via TFS. A workshop for those submitting full applications will be held in central London.

If you experience difficulties using TFS or have questions regarding its use, contact the Funding Service.


Phone: +44 (0) 1793 547 490

Assessment procedure

Proposals are assessed in a two stage process.

  1. Outline proposals are reviewed by the NC3Rs Grant Assessment Panel. Successful outline applicants are invited to submit a full application.
  2. Full applications are evaluated by international peer review and assessed by the NC3Rs Grant Assessment Panel. 

​The following criteria are taken into consideration when making the funding decisions:

  • Potential impact on the 3Rs.
  • Quality of the science.
  • Current or future importance of the proposal to medical, biological or veterinary research.
  • Strategy for promoting the proposed research and 3Rs outcomes within the scientific community.
  • Expertise and track record of the team.
  • Value for money.
  • Strategic relevance to the highlight notice (where appropriate).

In order to maintain the transparency and integrity of the peer review process we have adopted the UKRI principles of peer review. Please note the Referee and Panel assessment guidance and scoring criteria below.

Grant Assessment Panel

Funding Panel members are appointed in a personal capacity for three years, with the possibility of a further one or two years extension. We receive proposals from a wide range of disciplines. Additional members may be co-opted to each Panel, for one year, if additional expertise is required. A full list of current members and when their term ends is given below.

All Funding Panel members are required to declare any private, professional or commercial interests that give rise to, or could give rise to, a conflict of interest as detailed in the UKRI conflicts of interest policy.

Grant Assessment Panel members

Member name Institution Term ends
Professor Christopher George (Chair) Swansea University 2024
Dr Caroline Archer Exscientia 2026
Dr Adrian Biddle Queen Mary, University of London 2025
Dr Emma Blain  Cardiff University 2026
Dr Derek Brazil Queen's University Belfast 2024
Dr Yu-Mei Ruby Chang Royal Veterinary College 2026
Dr Ian Copple University of Liverpool 2025
Dr Darren Dahly University College Cork, Ireland 2024
Dr Philip Elks University of Sheffield 2026
Professor Colin Johnson University of Leeds 2024
Dr Jessica Martin Newcastle University 2025
Dr Patricia Muller Durham University 2024
Professor Peter Oliver  MRC Nucleic Acid Therapy Accelerator 2026
Dr Deepali Pal University of Bristol  2026
Dr Matt Parker University of Surrey 2026
Professor Gwendolen Reilly University of Sheffield 2026
Professor Ignacio Romero  The Open University  2025
Dr Emily Swindle University of Southampton 2025
Dr David Turner University of Liverpool 2026
Dr Joseph Turner Liverpool School of Tropical Medicine 2024
Dr Michel Vaillant Luxembourg Institute of Health 2025
Professor Stephen Wheatcroft University of Leeds 2026
Project grants next open October 2024.