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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

Impact stories

59 results

Supporting the Named Information Officer role

Current contact: Dr Ellen Forty,

Office-led project

Icons representing questions and answers within two speech bubbles

Replacing sentinel animals with environmental health monitoring

Current contact: Dr Khia Dobbinson,

Office-led project

RIVER Recommendations

Current contact: Dr Nathalie Percie du Sert,

Office-led project

Four bottles of culture medium, in a laboratory setting.

Supporting the uptake of replacement technologies

Current contact: Dr Ah-Lai Law,

Office-led project

Organ on a chip system. The chip is being held against a blue background with orange tweezers causing the channels on the chip to have an orange hue.

Review of animal use requirements in WHO biologics guidelines

Current contact: Dr Elliot Lilley,

Office-led project

Identifying and addressing challenges in fish vitellogenin assessment

Current contact: Dr Natalie Burden,

Office-led project

Re-evaluating the need for mAb chronic toxicity studies

Current contact: Dr Fiona Sewell,

Office-led project

Fig. 5. Integrated weight-of-evidence model modified from Chien et al. 2023

Rodent high-yield behavioural experiments

Current contact: Dr Chris Barkus,

Office-led project

A black mouse in a plastic cage, standing on paper nesting material.

The Experimental Design Assistant - EDA

Current contact: Dr Esther Pearl,

Office-led project

EDA diagram of an experiment representing a simple two-group comparison

Supporting the adoption of microphysiological systems for COVID research

Current contact: Dr Anthony Holmes,

Office-led project

Organ on a chip microphysiological system

Breeding and colony management

Current contact: Dr Esther Pearl,

Office-led project

Revision of the ARRIVE guidelines

Current contact: Dr Stephen Turnock,

Office-led project

The front cover of the ARRIVE guidelines publication

Human Tissue for Safety Pharmacology

Current contact: Dr Anthony Holmes,

Office-led project

Cell culture plate being removed from an incubator

Improving the predictive power of models for cancer research

Current contact: Dr Anthony Holmes,

Office-led project

Microscope image of cells glowing purple

Chair restraint training of non-human primates

Current contact: Dr Vicky Robinson,

Office-led project

Rodent models of stroke

Current contact: Dr Nathalie Percie du Sert,

Office-led project

Applying exposure science to increase the utility of non-animal data in efficacy and safety testing

Current contact: Dr Natalie Burden,

Office-led project

Opportunities to apply the 3Rs in the safety assessment of nanomaterials

Current contact: Dr Natalie Burden,

Office-led project

Maximising the success of bile duct cannulation studies

Current contact: Dr Natalie Burden,

Office-led project

Two white rats in an enriched cage containing cardboard tunnels and paper towels.

Review of the use of two species in regulatory toxicology studies

Current contact: Dr Elisa Passini,

Office-led project