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Impact stories

39 results

Novel approach to model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

Principal Investigator: Dr Carola Morell, University of Cambridge

Fellowship

Development of the chick embryo as a replacement for rodent models of tumour metastasis

Principal Investigator: Dr Anne Herrmann, University of Liverpool

Fellowship

Intestinal organoids as a replacement strategy to unravel early host intestinal epithelia interactions with whipworms

Principal Investigator: Dr Maria Duque Correa, Wellcome Trust Sanger Institute

Fellowship

Developing human organotypic perfused bioreactors for physiologically reproducible therapeutic compound screening of a tumour microenvironment

Principal Investigator: Dr Xiao Wan, University of Oxford

Fellowship

Interrogating the mouse visual system by automated analysis of voluntary behaviour

Principal Investigator: Dr Riccardo Storchi, University of Manchester

Fellowship

The establishment of left-right asymmetry in mammalian development

Principal Investigator: Dr David Turner, University of Liverpool

Fellowship

Training in hIPSC differentiation protocols to generate motor neuron-muscle cultures to replace rat models in study of mitochondria on axon physiology

Principal Investigator: Dr Mark Rigby, King's College London

Fellowship

Development of new experimental models to understand the genetic basis of allergic bronchopulmonary aspergillosis

Principal Investigator: Dr Sara Gago, University of Manchester

Fellowship

An industrial standard cancer drug development platform using human induced pluripotent stem cell technology

Principal Investigator: Dr Deepali Pal, Newcastle University

Fellowship

A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo

Principal Investigator: Dr Alessio Vagnoni

Fellowship

Molecularly Imprinted Nanoparticles (MIP NPs) as non-animal antibodies substitutes for detection of viruses

Principal Investigator: Dr Alessandro Poma, University College London

Fellowship

Contribution of autophagy to the maintenance, invasion and metastasis of melanoma stem-like sub populations.

Principal Investigator: Dr David Hill, Newcastle University

Fellowship

Generating zebrafish models of human eye movement disorders to replace mouse models

Principal Investigator: Dr Ivana Poparic, King's College London

Fellowship

Development of a sensitive in vitro system for anti-alpha-synuclein aggregation drug screening

Principal Investigator: Dr Maria Eugenia Herva Moyano, University of Cambridge

Fellowship

Signalling pathways of leukocyte migration in silico

Principal Investigator: Dr Juliane Liepe, Imperial College London

Fellowship

Refining the study of fatigue in mouse models of chronic liver disease

Principal Investigator: Dr Claire Richardson, Newcastle University

Fellowship

Dr Claire Richardson sat next to a laboratory cage of mice preparing to handle an animal using a tunnel

In vitro methods for replacement of current in vivo assays for development of drugs against heterogeneous cancer stem cell populations

Principal Investigator: Dr Adrian Biddle, Queen Mary University of London

Fellowship

The role of bronchoconstriction in the development of airway remodelling and its effects upon lung function

Principal Investigator: Dr Amanda Tatler, University of Nottingham

Fellowship

Optimisation of a flow-based human in vitro blood–brain barrier model to replace animal models for studying immunopathogenesis of viral brain infections

Principal Investigator: Dr Adjanie Patabendige, University of Liverpool

Fellowship