Implementing an MEA platform in human neurones for studying age-related neural network dysfunction and testing dietary interventions Principal Investigator: Dr Robert Williams, University of Bath Grants
Epithelial barrier model: in silico modelling and high throughput assessment Principal Investigator: Dr Malgorzata Wiench, University of Birmingham Grants
Optimising human stem cell models to decipher signals and responses during organogenesis Principal Investigator: Professor Jennifer Nichols, University of Edinburgh Grants
Mapping mitochondrial contact sites during neuronal ageing and neurodegeneration in Drosophila Principal Investigator: Dr Alessio Vagnoni, King's College London PhD Studentship
Development of novel tools to assay haematopoietic stem cell activity ex vivo Principal Investigator: Professor Marella de Bruijn, University of Oxford PhD Studentship
RoboHog: developing an in vitro gut model system of the porcine hindgut Principal Investigator: Dr Anthony Buckley, University of Leeds Grants
Developing a lung organoid signalome for real-time analysis of senescence-associated cellular cross talk Principal Investigator: Dr Alison John, Imperial College London Grants
A platform to investigate multi-tissue crosstalk mediated by exercise induced soluble factors released from human skeletal muscle Principal Investigator: Professor Mark Lewis, Loughborough University Grants
A novel in silico framework for early mammalian embryo development Principal Investigator: Dr David Richards, University of Exeter Grants
Developing a next generation in vitro 3D immune organoids system for studying vaccine-induced immune response and immune-ageing across the life-course Principal Investigator: Dr Qibo Zhang, University of Surrey Grants
Understanding mechanisms driving lung disease caused by environmental particulate matter Principal Investigator: Dr Nicholas Hannan, University of Nottingham Grants
A human ex vivo model of haemostasis: A replacement for rodent tail bleeding assays Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University Grants
Development of an in vitro system that mimics B and T helper cell responses in porcine lymph nodes Principal Investigator: Dr Wilhelm Gerner, The Pirbright Institute Project grant
Study of human late fetal lung tissue and 3D in vitro organoids to replace and reduce animals in lung developmental research Principal Investigator: Dr Marko Nikolić, University College London PhD Studentship
A high-throughput-compatible animal-cell-free miniaturised thymic organoid model for thymus biology studies and in vitro T cell production Principal Investigator: Professor Clare Blackburn, University of Edinburgh Grants
Production of a Human Growth Plate Organ-Chip Model of Skeletal Development Principal Investigator: Professor Martin Knight, Queen Mary University of London Grants
In vitro digestibility - reducing animal use whilst meeting the demand to evaluate alternative proteins Principal Investigator: Professor John Brameld, University of Nottingham Grants
Developing a complex in vitro airway model to study respiratory viral pathogenesis, lung macrophage function and herpesviral vaccine vectors in pigs Principal Investigator: Dr Gyorgy Fejer, University of Plymouth Grants
Developing a human vascularised pancreatic islet on a chip - VIOC Principal Investigator: Dr Victoria Salem, Imperial College London Grants
Novel in vitro platform to study molecular mechanisms of neurotransmitter release and synaptic plasticity Principal Investigator: Professor Kirill Volynski, University College London Grants