Development of a new human cell genotoxicity assay to reduce the use of live animals in drug development Principal Investigator: Professor Richard Walmsley, University of Manchester Project grant
Embryonic stem cell-derived cardiomyocytes as a model system for cardiac investigations Principal Investigator: Professor Sian Harding, Imperial College London Project grant
Development of an air-interface in vitro organ culture model (IVOC) of bovine respiratory epithelium Principal Investigator: Dr Alexander Tucker, University of Cambridge Project grant
Development of replacement in vitro assays for the quantification of clostridial vaccine antigens Principal Investigator: Dr Keith Redhead, Project grant
The development of a cell-based diabetic wound bioassay Principal Investigator: Professor David Thomas, Cardiff University Project grant
Replacement of the mouse bioassay: Development of SPE and LC-MS for detection of paralytic shellfish poisoning toxins Principal Investigator: Dr Elizabeth Turrell, Marine Scotland Science Project grant
Maintenance of Lutzomyia longipalpis colonies using an artificial membrane blood-feeding method Principal Investigator: Professor Richard Ward, Keele University Project grant
Cell lines for prediction of drug metabolism and toxicity in man Principal Investigator: Professor Charles Wolf, Dundee Technopol CXR Biosciences Ltd Project grant
The reduction in animal usage by multiple antigen immunisation schedules Principal Investigator: Dr Simon Smith, University of Sheffield Project grant
Development of a new tissue-friendly head implant for use in awake, behaving monkey studies Principal Investigator: Professor Roger Lemon, University College London Project grant
The behaviour of laboratory mice as an indicator of welfare state in genetically modified mice Principal Investigator: Professor Christine Nicol, University of Bristol Project grant
A novel approach to the preclinical assessment of novel anti-cancer drugs Principal Investigator: Professor Michael Bibby, University of Bradford Project grant
Neoplasia and pain in laboratory animals Principal Investigator: Dr John Roughan, Newcastle University Project grant
Supporting the adoption of microphysiological systems for COVID research Current contact: Dr Anthony Holmes, Office-led project
Improving the predictive power of models for cancer research Current contact: Dr Anthony Holmes, Office-led project
Chair restraint training of non-human primates Current contact: Dr Vicky Robinson, Office-led project