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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

Impact stories

40 results

Using zebrafish for pre-clinical brain haemorrhage research

Principal Investigator: Professor Stuart Allan, University of Manchester

PhD Studentship

A non-mammalian model for neurofunctional studies of vertebrate dopamine signalling

Principal Investigator: Dr Jonathan McDearmid, University of Leicester

PhD Studentship

Developing a model for the study of respiratory inflammation in the zebrafish

Principal Investigator: Professor Margaret Dallman, Imperial College London

Strategic grant

Motor neuron regeneration in larval zebrafish

Principal Investigator: Professor Catherina Becker, University of Edinburgh

PhD Studentship

Contribution of autophagy to the maintenance, invasion and metastasis of melanoma stem-like sub populations.

Principal Investigator: Dr David Hill, Newcastle University

Fellowship

Generating zebrafish models of human eye movement disorders to replace mouse models

Principal Investigator: Dr Ivana Poparic, King's College London

Fellowship

Replacing rodent models for investigating the influence of the microbiome upon innate immune responses and resistance to pathogens

Principal Investigator: Dr Rachel Lawrence, Royal Veterinary College

PhD Studentship

Novel approaches to immortalise salmon fish cells

Principal Investigator: Dr Bertrand Collet, Marine Scotland Science

Pilot study grant

Training and teaching resources to underpin implementation of refinement of in vivo studies

Principal Investigator: Professor Paul Flecknell, Newcastle University

Infrastructure grant

Professor Paul Flecknell giving a speech on a podium

Finding effective analgesics in zebrafish by analysing effects on the nervous system (CNS)

Principal Investigator: Professor Catherina Becker, University of Edinburgh

Pilot study grant

Live imaging of mucosal and vascular inflammation in zebrafish in response to a high cholesterol diet

Principal Investigator: Professor Margaret Dallman, Imperial College London

PhD Studentship

Investigation of behavioural and physiological responses to fin-clipping in zebrafish

Principal Investigator: Ms Gidona Goodman, University of Edinburgh

Pilot study grant

The detection, assessment and alleviation of pain in laboratory zebrafish

Principal Investigator: Dr Lynne Sneddon, University of Liverpool

Project grant

Assessing welfare in fish: the answer is in the water!

Principal Investigator: Dr Ioanna Katsiadaki, Centre for Environment Fisheries and Aquaculture Science

Project grant

Zebrafish behavioural assays to identify genetic mechanisms underlying drug seeking and addiction

Principal Investigator: Dr Caroline Brennan, Queen Mary University of London

Project grant

Validating a sexual development test using the 3-spined stickleback for addressing the 3Rs in fish toxicity testing

Principal Investigator: Dr Ioanna Katsiadaki, Centre for Environment Fisheries and Aquaculture Science

Project grant

Development of a mechanistically informative genome-wide, replacement chemicals screening technology

Principal Investigator: Professor Andrew Cossins, University of Liverpool

Project grant

Breeding and colony management

Current contact: Dr Esther Pearl

Office-led project

Applying the threshold approach in fish acute toxicity studies

Current contact: Dr Natalie Burden

Office-led project

Assessing the need for chronic fish studies on formulated pesticides

Current contact: Dr Natalie Burden

Office-led project