Development of Galleria mellonella as a replacement preclinical model for snakebite envenoming to reduce the need for murine models Principal Investigator: Dr Rachel Clare, Liverpool School of Tropical Medicine Project grant
Generation of vascularised immunocompetent retinal assembloids from human pluripotent stem cells Principal Investigator: Professor Majlinda Lako, Newcastle University Project grant
Developing Human Skin Microbiota Models to Replace Rodent Studies and Explore Host-Microbe Interactions Principal Investigator: Dr Holly Wilkinson, University of Hull Project grant
Revolutionising relative bioavailability testing: Using AI-PAT to eliminate animal models Principal Investigator: Professor Hannah Batchelor, University of Strathclyde Strategic grant
Bioreactor infrastructure for organoid culture in human models of reproductive diseases Principal Investigator: Professor Andrew Blanks, University of Warwick Strategic grant
Novel bioprinters for 3D In Vitro Models (3D-IV) Principal Investigator: Professor Kenneth Dalgarno, Newcastle University Strategic grant
Establishing a core infrastructure for enhancing gut health, disease and microbiome research using advanced non-animal models Principal Investigator: Dr Tamás Korcsmáros, Imperial College London Strategic grant
DAR3T: Data Analysis of 3Rs Tools Principal Investigator: Professor Crispin Miller, University of Glasgow Strategic grant
A world-class in vitro models facility for the UK community, reducing the barriers to adoption to drive animal replacement Principal Investigator: Professor Hazel Screen, Queen Mary University of London Strategic grant
Scaling up human pluripotent stem cell delivery and distribution facilitating reduction in animal use Principal Investigator: Professor Kate Storey, University of Dundee Strategic grant
A core facility for human induced pluripotent stem cells for neurological disease Principal Investigator: Professor Selina Wray, University College London Strategic grant
Animal free alternatives to the study of nutrition in early pregnancy Principal Investigator: Professor Roger Sturmey, University of Hull PhD Studentship
Anesthesia-on-chip: Modelling the impact of fetal anesthesia on neural development Principal Investigator: Dr Gabriel Galea, University College London PhD Studentship
Novel in vitro endometrial scaffolds to investigate embryo implantation and early development Principal Investigator: Dr Peter Rugg-Gunn, Babraham Institute Cambridge PhD Studentship
Establishing a physiologically relevant in vitro model of blood development Principal Investigator: Dr Victor Hernandez , Brunel University Project grant
Characterisation of antibodies and affinity reagents to promote the adoption of robust and reproducible non-animal reagents Principal Investigator: Dr Harvinder Virk, University of Leicester Strategic grant
Revolutionizing micro-surgical training by reducing and replacing animal dependency through synthetic biomimetic 3D printed blood vessels Principal Investigator: Professor Deepak Kalaskar, University College London Strategic grant
Validation of non-animal derived products for stem cell-derived breast cancer organoid models Principal Investigator: Dr Cinzia Allegrucci, University of Nottingham Strategic grant
Direct replacement of secondary antibodies by affimer proteins in lateral flow devices Principal Investigator: Dr Christian Tiede, University of Leeds Strategic grant
An animal-free future for heart research: functional characterisation of novel refined human engineered heart tissue Principal Investigator: Professor Helen Maddock, Coventry University Strategic grant