Replacing Alzheimer's disease (AD) - Down syndrome (DS) mice with fly models Principal Investigator: Dr Frances Wiseman, University College London PhD Studentship
Fully humanised 3D vascular perfused model for breast cancer modelling and therapeutic screening Principal Investigator: Professor Valerie Speirs, University of Aberdeen Partnerships and impact awards
Galleria mellonella as an infection model for viral pathogens Principal Investigator: Professor Richard Titball, University of Exeter Project grant
Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways Principal Investigator: Dr Daniel Neill, University of Liverpool PhD Studentship
Reducing number of mice required for drug testing via development of first in vitro automated screening platform of injured mammalian brain Principal Investigator: Dr Veronique Miron, University of Edinburgh PhD Studentship
Advanced in vitro and in silico models to predict and prevent deep venous thrombosis Principal Investigator: Dr Alessio Alexiadis, University of Birmingham PhD Studentship
Developing a rapid method for identification of key proteins that define tissues to create an array of tissue-specific hydrogels for human-relevant in vitro 3D culture Principal Investigator: Professor Cathy Merry, University of Nottingham Technologies to tools grant
Transfer of the epicardial-cardiac organotypic culture model to support the ex vivo screening of gene therapy candidates Principal Investigator: Dr Paola Campagnolo, University of Surrey Partnerships and impact awards
Assessing the relevance of Galleria mellonella to antibiotic drug discovery for pulmonary infections Principal Investigator: Dr James Mason, King's College London Partnerships and impact awards
An in vivo genetic screen of lung function candidate genes using tissue specific RNAi in Drosophila melanogaster Principal Investigator: Dr Marios Georgiou, University of Nottingham PhD Studentship
Replacing the need for patient-derived xenografts and matrigel organoid culture as preclinical models for breast cancer Principal Investigator: Dr Robert Clarke, The University of Manchester Partnerships and impact awards
Platform to phenotype liver metabolic disorders Principal Investigator: Professor Ludovic Vallier, University of Cambridge Technologies to tools grant
Translating microvascularised chips of a nephrotoxicity model Principal Investigator: Dr Julien Gautrot, Queen Mary University of London Technologies to tools grant
From ageing to space travel: Developing an organotypic model of skeletal tissue disuse for understanding degeneration in altered environments Principal Investigator: Dr Alexandra Iordachescu, University of Birmingham Fellowship
Systems modelling age-related changes in the maintenance of dermal extra-cellular matrix: mechanisms and interventions Principal Investigator: Dr Daryl Shanley, Newcastle University Project grant
Validating alternative models to cats and dogs for heartworm drug testing Principal Investigator: Dr Joseph Turner, Liverpool School of Tropical Medicine Project grant
Drosophila model for muscular pain Principal Investigator: Dr Olga Baron, King's College London Fellowship
Validating CombiDART in the agrochemical sector Contractor: Professor Alison Woollard, University of Oxford CRACK IT Solution
Characterising Mycobacterium tuberculosis in the human lung; developing new tools for antimicrobial drug discovery through the SH-TBL clinical trial Principal Investigator: Professor Simon Waddell, University of Sussex PhD Studentship
An alternative approach for assessing drug-induced seizures, using non-protected larval zebrafish Principal Investigator: Professor Charles Tyler, University of Exeter PhD Studentship