Refining an in vitro system of predictive biomarkers of in vivo liposome efficacy Principal Investigator: Dr Andrew Devitt, Aston University PhD Studentship
Using zebrafish for pre-clinical brain haemorrhage research Principal Investigator: Professor Stuart Allan, University of Manchester PhD Studentship
Building brains in a dish - using ES cells to understand brain development Principal Investigator: Dr John Mason, University of Edinburgh PhD Studentship
In silico human-based methodologies for evaluation of drug cardiac safety and efficacy Principal Investigator: Professor Blanca Rodriguez, University of Oxford Infrastructure grant
Metaboderm: 3D hiPSC derived skin model and in-silico skin modelling of metabolism Contractor: Professor Lyle Armstrong, Newcells Biotech Ltd CRACK IT Challenge
InMutaGene: A human IPS cell model for gene therapy vector safety evaluation Contractor: Dr Manfred Schmidt, GeneWerk GmbH CRACK IT Challenge
A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo Principal Investigator: Dr Alessio Vagnoni Fellowship
Development of a novel cell based bitter taste assessment assay Principal Investigator: Dr Afzal Rahman Mohammed, Aston University PhD Studentship
A bovine alveolus model to replace cattle in the study of host-pathogen interactions in bovine tuberculosis Principal Investigator: Professor Mark Chambers, University of Surrey Strategic grant
Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration Principal Investigator: Dr Tomas Bellamy, University of Nottingham PhD Studentship
A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research Principal Investigator: Professor Cathy Merry, University of Nottingham Project grant
Development and characterisation of a human ex vivo model of aneurysm Principal Investigator: Dr Jason Johnson, University of Bristol PhD Studentship
Portable bioluminescence test for botulinum neurotoxin Contractor: Dr Gregory Stevens, University of Freiburg CRACK IT Solution
Affimers: animal free alternatives to antibodies Contractor: Philip Cotrel, Avacta Life Sciences CRACK IT Solution
Probing in vivo parasite biology in vitro Principal Investigator: Professor Aaron Maule, Queen's University Belfast Project grant
Modelling liver fibrosis using human Induced Pluripotent Stem Cells Principal Investigator: Dr Ludovic Vallier, University of Cambridge Project grant
An organotypic model of bronchial dysplasia Principal Investigator: Dr Frank McCaughan, University of Cambridge PhD Studentship
C. elegans model to unravel the role of Klotho in ion metabolism and ageing Principal Investigator: Dr Tarja Kinnunen, University of Huddersfield PhD Studentship
Enhancing mouse whole embryo culture for use in birth defects research Principal Investigator: Professor Andrew Copp, University College London PhD Studentship
Human stem cell derived neurones and astrocytes as an in vitro model of human prion infection and replication Principal Investigator: Professor Siddharthan Chandran, University of Edinburgh Project grant