Using molecular simulation to improve prediction of drug export Principal Investigator: Dr Philip Biggin, University of Oxford PhD Studentship
SyRF: the CAMARADES/NC3Rs in vivo systematic review and meta-analysis facility Principal Investigator: Professor Malcolm Macleod, University of Edinburgh Infrastructure grant
Training and teaching resources to underpin implementation of refinement of in vivo studies Principal Investigator: Professor Paul Flecknell, Newcastle University Infrastructure grant
Reducing the number of non-human primates in research by developing a rodent model of selective attention Principal Investigator: Dr Samuel Solomon, University College London Pilot study grant
Finding effective analgesics in zebrafish by analysing effects on the nervous system (CNS) Principal Investigator: Professor Catherina Becker, University of Edinburgh Pilot study grant
Live imaging of mucosal and vascular inflammation in zebrafish in response to a high cholesterol diet Principal Investigator: Professor Margaret Dallman, Imperial College London PhD Studentship
Using human pluripotent stem cell-derived cardiomyocytes to test drug cardiac toxicity Contractor: Dr Tamer Mohammed, CRACK IT Solution
Using C. elegans to produce proteins from parasitic nematodes for research and therapeutic use Principal Investigator: Dr David Weinkove, Durham University Pilot study grant
Signalling pathways of leukocyte migration in silico Principal Investigator: Dr Juliane Liepe, Imperial College London Fellowship
PREDART: An integrative Dictyostelium, C. elegans and zebrafish approach to assess DART Contractor: Professor Raymond Peters, Institute for Risk Assessment Sciences/ Toxicology, U…, CRACK IT Challenge
Live real-time imaging of life-threatening invasive fungal infections Principal Investigator: Dr Donna MacCallum, University of Aberdeen Pilot study grant
Investigating tuberculosis by engineering human granulomas Principal Investigator: Dr Liku Tezera, University of Southampton Pilot study grant
Development of computational models of bone formation and resorption to predict changes in bone in preclinical intervention studies Principal Investigator: Dr Ilaria Bellantuono, University of Sheffield Project grant
Assessing cumulative severity in macaques used in neuroscience research Principal Investigator: Professor Melissa Bateson, Newcastle University Project grant
Imprecision and importance: Probabilistic graphical models in toxicology Principal Investigator: Dr Jonathan Pitchford, University of York Strategic grant
Quantifying the behavioural and facial correlates of pain in laboratory macaques Principal Investigator: Dr Sarah-Jane Vick, University of Stirling Project grant
An early screen for emetic liability of NCEs using the amoeba Dictyostelium Contractor: Professor Robin Williams, CRACK IT Solution
Uncertainty and confidence in applying mathematical models and in vitro data in toxicological safety assessments Principal Investigator: Dr John Gosling, University of Leeds Strategic grant