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NC3Rs | 20 Years: Pioneering Better Science

Search our 3Rs resource library

Use the filters below to narrow down our resources to those relevant to your role, the model you are interested in, or by topic area. Filters are best used by combining two or more to narrow down the results.

27 results

Join our community of researchers, developers, industry and regulatory end-users working together to accelerate the use of new approach methodologies.

Graphic showing some of the range of applications of NAMs

Learn more about what NAMs are and how they can be applied to progress the 3Rs.

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Projects to ensure that the in vivo tests involved in ED assessment are as robust as possible, particularly focusing on aquatic species.....

Zebra fishes in tank

Quarterly e-newsletter to keep the scientific community updated on news from the NC3Rs Toxicology and Regulatory Sciences programme.

A white icon of an envelope on a purple background.

Reducing and refining acute toxicity tests in the pharmaceutical and chemicals industries.

A white mouse on a technician's gloved hands

Providing an evidence base to refine and reduce the use of vertebrates in (regulatory) ecotoxicology studies

A group of young rainbow trout

Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies

A lister hooded rat (black head white body) seen in a standard rat housing cage. The rat is standing on a plastic box and is looking out of the open cage lid.

Guidance on reducing or refining animal use for studies with cardiovascular, central nervous system and respiratory functional measurements.

A beagle at an indoor play area

Paper clarifies that the forced swim test is not a regulatory requirement for the development of new antidepressants (NC3Rs & MHRA project).

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