Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
![Black mouse sitting on open hands. The technician is wearing a blue coveralls and blue medical grade gloves.](/sites/default/files/styles/image_16_9/public/2021-10/Black%20mouse%20sitting%20on%20gloved%20hands.jpg?itok=IS6JBJ2J)
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
![Two scientists look into microscopes](/sites/default/files/styles/image_16_9/public/2022-01/Two%20happy%20scientists%20look%20in%20microscopes.jpg?h=4e3b394f&itok=_T846sEb)
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
![Two researchers look at a sample in a Petri dish](/sites/default/files/styles/image_16_9/public/2022-01/Two%20researchers%20look%20at%20a%20sample%20in%20a%20Petri%20dish.jpg?itok=9cZWFsQr)
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
![Two white rats in an enriched cage containing cardboard tunnels and paper towels.](/sites/default/files/styles/image_16_9/public/2021-07/Rat_cage_0_0.jpg?itok=k7fyyi6d)
Latest news
We have committed over £1M towards the development of non-animal methods.
![Researchers having a conversation in the lab](/sites/default/files/styles/image_16_9/public/2022-01/Scientists%20talking%20in%20lab%20%28research%20culture%29.jpg?h=582151e0&itok=ta1eRAwh)
We look back at 20 years of innovation in the 3Rs in an AI special issue of The Biologist, the magazine from the Royal Society of Biology.
![An article in the Biologist magazine.](/sites/default/files/styles/image_16_9/public/2025-01/Biologist-article_1.jpg?h=8f7c2053&itok=2F-wuamr)
21 awards have been supported with DSIT funding to accelerate the uptake of non-animal approaches and replace animal-derived products in research and testing.
![Composite image showing examples of non-animal methods and products that can be non-animal derived, from left to right, antibodies, cell culture flask, computer screen and scaffold for 3D cell culture.](/sites/default/files/styles/image_16_9/public/2024-12/NAMs%20composite.png?itok=vnKZ7gmm)
Hear how lecturers at the University of Nottingham are using the Experimental Design Assistant (EDA) as an engaging and practical way to teach experimental design.
![Early career researchers at a workshop on experimental design.](/sites/default/files/styles/image_16_9/public/2024-12/Experimental%20design%20workshop_summer%20school%202024.jpg?itok=q1QvSuGk)
The ARRIVE study plan is a freely available resource to assess the rigour and improve the transparency of planned animal research.
![The ARRIVE study plan](/sites/default/files/styles/image_16_9/public/2024-10/Study%20plan%20dissemination%20image.png?itok=hHVZfLzB)
£10M will be available to support interdisciplinary research clusters.
![Organ-on-chip device](/sites/default/files/styles/image_16_9/public/2024-09/Organ%20on%20a%20chip%20%28Shutterstock%29.jpg?itok=-1_zBqgL)
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
![A visual representation of a network](/sites/default/files/styles/image_16_9/public/2023-03/CRACK%20IT%20mega%20Challenge%20virtual%20dog%202022.png?itok=bIzu5Wfg)