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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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Keep up to date with the latest news from the NC3Rs, including the researchers we fund. Follow us on social media and subscribe to our newsletter to get the latest updates directly.

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Our Experimental Design Assistant (EDA) helps you to design robust and meaningful animal experiments. With a wealth of information, features and tools, here are our tips to help you make the most of the EDA.

A diagram showing how the EDA can be used to represent a two group comparison experiment. The EDA works by dragging and dropping 'nodes' which appear as coloured shapes. These are then connected with arrows or ‘links’ showing how different parts of an experiment relate to each other. The EDA then uses computer-based logical reasoning to provide feedback on the experimental design.

Our latest impact stories feature three replacement approaches developed through NC3Rs funding that were the first in vitro models validated to replace animal use for specific experiments in their research areas.

Three sets of icons. Left to right: Bone, cancer cells, 96 well plate.

We are launching a new funding opportunity through a strategic collaboration with BBSRC to help researchers commercialise their 3Rs tools and technologies.

ICURe Innovate UK and BBSRC

NC3Rs Programme Manager Dr Elliot Lilley reflects on the united vision that drove the success of our project to embed the 3Rs in quality, safety and efficacy testing of vaccines and biological therapeutics.

Portrait of Dr Elliot Lilley

We are partnering with Pint of Science to invite you to learn more about the science behind replacing animals in research.

Icons representing replacement approaches.

Hear from the NC3Rs NAMs Advisory Group as they discuss their recent paper on how to overcome the hurdles to embedding new approach methodologies (NAMs) in chemical and drug safety assessment.

Three images representing NAMs: a laboratory flask, an environmental landscape and a computer-designed molecule.

Bringing together oncology researchers to establish collaborations and catalyse the uptake of 3Rs technologies for cancer research.

A graphic showing a network of circles, the three in the centre feature icons depicting cancer cells, chemotherapy drugs and DNA

Discover how the NC3Rs works to address the use of dogs in research and replace the use of animals in toxicity testing with non-animal methods, two topics being debated in Parliament later today.

Portrait of Dr Vicky Robinson, Chief Executive, NC3Rs.

Explore papers sharing 3Rs methods and technologies published on the NC3Rs F1000 Gateway – an open access platform for NC3Rs grant holders to showcase their research and maximise the 3Rs impact of their work.

The NC3Rs F1000 Gateway homepage.