A recent publication in the journal mAbs “Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges” highlights ways to reduce animal use in the development of monoclonal antibody (mAb) biosimilars.
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Today is World Asthma Day. To mark this important event our Chief Executive Dr Vicky Robinson is using her monthly blog to highlight some of the work that we have been leading over the last ten years in partnership with the UK’s asthma research
We are pleased to announce a new strategic award to Professor Alex Thiele, Newcastle University, for a project aimed at refining the design of cranial implants used in neuroscience studies with macaques, in order to improve the welfare of these
The NC3Rs and Safety Pharmacology Society (SPS) have just published the paper ‘Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies’.
The annual Pint of Science festival will be taking over pubs across the country next month to host evenings where scientists discuss their research over a proverbial pint.
They say you can’t teach an old dog new tricks. But what about scientists and new procedures?
We are launching a new series of monthly blog posts by our Chief Executive, Dr Vicky Robinson.
A study published in Nature reported the creation of brain organoids that mimic the developing human cerebrum for the very first time.
A new study has shown that introducing physiologic cues to the in vitro culture of hepatocyte-like cells (HLCs) makes them a more relevant hepatocyte model that can be used in non-animal liver toxicity testing.
The work of the NC3Rs is increasingly international. We continue to maintain our focus as the UK’s national centre on the 3Rs, but as our portfolio of office-led data sharing activities has grown, so too has the number of overseas partners that we
A study describes a new method to grow a drug resistant sub-population of cancer stem cells (CSCs) in vitro, providing an opportunity to screen compounds that target these cells using fewer animals.
Three projects have each been awarded £30,000 seed funding, through the NC3Rs CRACK IT Solutions partnering programme, to support collaborations which will help develop, validate and test technologies with 3Rs potential.
Researchers at the University of York are seeking partners with expertise in mammalian cell culture to develop novel mathematical approaches for in vitro to in vivo extrapolation.
Latest CRACK IT Challenges: funding innovative technologies with 3Rs benefits and business potential
Six teams have been awarded funding in Phase 1 of the latest NC3Rs CRACK IT Challenges competition, a challenge-led competition run in collaboration with the UK’s innovation agency, Innovate UK, using its Small Business Research Initiative (SBRI).
Three pieces of outstanding published research with 3Rs impacts have been given awards in this year’s 3Rs Prize competition, run by the NC3Rs, and sponsored by GlaxoSmithKline (GSK).
A new e-learning training package designed to help researchers and animal care staff identify signs of good and poor welfare in laboratory animals has been launched online.
Fish are commonly used in experiments to identify environmental hazards and pollutants in water.
Bovine tuberculosis (bTB) is one of the biggest challenges facing the cattle farming industry in the UK.
The ARRIVE guidelines were launched in 2010, and since their publication the scientific community have been using the guidelines to improve the reporting of animal research.
Invertebrates such as Drosophila melanogaster (the fruit fly) are used extensively in research on complex biological processes and disease mechanisms.
