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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

Impact stories

63 results

Supporting the Named Information Officer role

Current contact: Dr Ellen Forty

Office-led project

Icons representing questions and answers within two speech bubbles

Supporting 3Rs approaches in biologicals testing

Current contact: Dr Elliot Lilley

Office-led project

Replacing sentinel animals with environmental health monitoring

Current contact: Dr Khia Dobbinson

Office-led project

Review of the value of urinalysis assessments in toxicity studies

Current contact: Dr Fiona Sewell

Office-led project

Review of the use of two species in regulatory toxicology studies: Phase II - molecules following ICH M3(R2)

Office-led project

RIVER Recommendations

Current contact: James Barker

Office-led project

Four bottles of culture medium, in a laboratory setting.

Assessing the resource and animal use implications of new EU REACH endocrine disruptor assessment information requirements

Current contact: Dr Natalie Burden

Office-led project

Accelerating the uptake of non-animal derived antibodies

Current contact: Dr Rachel Eyre

Office-led project

Review of animal use requirements in WHO biologics guidelines

Current contact: Dr Elliot Lilley

Office-led project

Identifying and addressing challenges in fish vitellogenin assessment

Current contact: Dr Natalie Burden

Office-led project

Forced swim test in rodents

Current contact: Dr Vicky Robinson

Office-led project

Re-evaluating the need for mAb chronic toxicity studies

Current contact: Dr Fiona Sewell

Office-led project

Fig. 5. Integrated weight-of-evidence model modified from Chien et al. 2023

Rodent high-yield behavioural experiments

Current contact: Dr Chris Barkus

Office-led project

A black mouse in a plastic cage, standing on paper nesting material.

Review of the use of two species in regulatory toxicology studies

Current contact: Dr Elisa Passini

Office-led project

The Experimental Design Assistant - EDA

Current contact: Dr Esther Pearl

Office-led project

EDA diagram of an experiment representing a simple two-group comparison

Supporting the adoption of microphysiological systems for COVID research

Current contact: Dr Anthony Holmes

Office-led project

Organ on a chip microphysiological system

Breeding and colony management

Current contact: Dr Esther Pearl

Office-led project

Revision of the ARRIVE guidelines

Current contact: Dr Stephen Turnock

Office-led project

The front cover of the ARRIVE guidelines publication

Human Tissue for Safety Pharmacology

Current contact: Dr Anthony Holmes

Office-led project

Cell culture plate being removed from an incubator

Improving the predictive power of models for cancer research

Current contact: Dr Anthony Holmes

Office-led project

Microscope image of cells glowing purple