A 3Rs approach to tumour metastasis: investigating the role of cancer stem cells in metastasis using an in vitro microfluidic model Principal Investigator: Dr Adrian Biddle, Queen Mary University of London PhD Studentship
Modelling Candida albicans infection of the human gut using human intestinal organoid cultures Principal Investigator: Dr Silvia Gratz, University of Aberdeen PhD Studentship
Maternal immune activation: advancing from rodents to humans through a development of a hIPSC model to study gene x environment interactions Principal Investigator: Dr Anthony Vernon, King's College London PhD Studentship
Development of novel models of kidney damage using induced human pluripotent stem cells Principal Investigator: Dr Derek Brazil, Queen's University Belfast PhD Studentship
Fusogenic liposomes: the innovative delivery of compounds into human platelets to reduce animal use in platelet research Principal Investigator: Dr Alice Pollitt, University of Reading PhD Studentship
Replacement of animal models of cardiac arrest and resuscitation strategies using a computer simulation Principal Investigator: Professor Jonathan Hardman, University of Nottingham PhD Studentship
Replacing Alzheimer's disease (AD) - Down syndrome (DS) mice with fly models Principal Investigator: Dr Frances Wiseman, University College London PhD Studentship
Fully humanised 3D vascular perfused model for breast cancer modelling and therapeutic screening Principal Investigator: Professor Valerie Speirs, University of Aberdeen Skills and Knowledge Transfer grant
Galleria mellonella as an infection model for viral pathogens Principal Investigator: Professor Richard Titball, University of Exeter Project grant
Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways Principal Investigator: Dr Daniel Neill, University of Liverpool PhD Studentship
Reducing number of mice required for drug testing via development of first in vitro automated screening platform of injured mammalian brain Principal Investigator: Dr Veronique Miron, University of Edinburgh PhD Studentship
Advanced in vitro and in silico models to predict and prevent deep venous thrombosis Principal Investigator: Dr Alessio Alexiadis, University of Birmingham PhD Studentship
Developing a rapid method for identification of key proteins that define tissues to create an array of tissue-specific hydrogels for human-relevant in vitro 3D culture Principal Investigator: Professor Cathy Merry, University of Nottingham Technologies to Tools grant
Transfer of the epicardial-cardiac organotypic culture model to support the ex vivo screening of gene therapy candidates Principal Investigator: Dr Paola Campagnolo, University of Surrey Skills and Knowledge Transfer grant
Assessing the relevance of Galleria mellonella to antibiotic drug discovery for pulmonary infections Principal Investigator: Dr James Mason, King's College London Skills and Knowledge Transfer grant
An in vivo genetic screen of lung function candidate genes using tissue specific RNAi in Drosophila melanogaster Principal Investigator: Dr Marios Georgiou, University of Nottingham PhD Studentship
Replacing the need for patient-derived xenografts and matrigel organoid culture as preclinical models for breast cancer Principal Investigator: Dr Robert Clarke, The University of Manchester Skills and Knowledge Transfer grant
Platform to phenotype liver metabolic disorders Principal Investigator: Professor Ludovic Vallier, University of Cambridge Technologies to Tools grant
Translating microvascularised chips of a nephrotoxicity model Principal Investigator: Dr Julien Gautrot, Queen Mary University of London Technologies to Tools grant
From ageing to space travel: Developing an organotypic model of skeletal tissue disuse for understanding degeneration in altered environments Principal Investigator: Dr Alexandra Iordachescu, University of Birmingham Fellowship