Development of a minimally-invasive ultrasound guided rat myocardial infarction model to replace the gold standard invasive thoracotomy approach Principal Investigator: Dr Mark MacAskill, University of Edinburgh PhD Studentship
Using a novel human 3D spheroid model to study mechanisms and therapeutics for vascular calcification Principal Investigator: Professor Cathy Shanahan, King's College London PhD Studentship
Animal free alternatives to the study of nutrition in early pregnancy Principal Investigator: Professor Roger Sturmey, University of Hull PhD Studentship
Characterisation of antibodies and affinity reagents to promote the adoption of robust and reproducible non-animal reagents Principal Investigator: Dr Harvinder Virk, University of Leicester Strategic grant
An animal-free future for heart research: functional characterisation of novel refined human engineered heart tissue Principal Investigator: Professor Helen Maddock, Coventry University Strategic grant
BetaCell Birmingham Principal Investigator: Dr Ildem Akerman, University of Birmingham Strategic grant
A computational model of fibrosis and the cardiac conduction system: the next generation of virtual heart models for research and teaching Principal Investigator: Dr Michael Colman, University of Leeds PhD Studentship
Development and disease modelling in engineered vascular tissues Principal Investigator: Professor Manuel Mayr, Imperial College London PhD Studentship
Identification of the molecular and cellular mechanisms driving cardiac fibrosis: A novel ex vivo approach to target identification and validation Principal Investigator: Dr Lee Borthwick, Newcastle University PhD Studentship
A platform to investigate multi-tissue crosstalk mediated by exercise induced soluble factors released from human skeletal muscle Principal Investigator: Professor Mark Lewis, Loughborough University Project grant
High fidelity computational approaches to exploit new structures of cardiac ion channels Principal Investigator: Dr Andrew Leach, University of Manchester PhD Studentship
Modelling of thrombus dynamics in a microfluidic 'vasculature' Principal Investigator: Dr Nicola Mutch, University of Aberdeen PhD Studentship
Targeted protein degradation as a novel approach to study protein function in human platelets Principal Investigator: Professor Ingeborg Hers, University of Bristol PhD Studentship
Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity Principal Investigator: Dr Grant Wheeler, University of East Anglia PhD Studentship
Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias Principal Investigator: Dr Katja Gehmlich, University of Birmingham PhD Studentship
Myocardial slices to study cardiovascular disease in vitro Principal Investigator: Professor Cesare Terracciano, Imperial College London Project grant
Development and characterization of a novel endothelialized in vitro model of human atherothrombosis Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University PhD Studentship
Fusogenic liposomes: the innovative delivery of compounds into human platelets to reduce animal use in platelet research Principal Investigator: Dr Alice Pollitt, University of Reading PhD Studentship
Transfer of the epicardial-cardiac organotypic culture model to support the ex vivo screening of gene therapy candidates Principal Investigator: Dr Paola Campagnolo, University of Surrey Partnerships and impact awards
An alternative approach for assessing drug-induced seizures, using non-protected larval zebrafish Principal Investigator: Professor Charles Tyler, University of Exeter PhD Studentship