Building confidence in non-protected zebrafish embryo-larvae as a viable alternative to mammalian DART assessment Principal Investigator: Dr Jonathan Ball, University of Exeter PhD Studentship
Novel, biologically relevant, in vitro model of the blood-brain tumour barrier (BBTB) Principal Investigator: Dr David Dickens, University of Liverpool PhD Studentship
Replacing Mouse Immunotherapy Models with Human Colorectal Cancer Organoid - T Cell Cultures Principal Investigator: Professor Awen Gallimore, Cardiff University PhD Studentship
Manipulating cholangiocarcinoma immune-phenotype in a patient derived precision-cut tumour model to improve immune checkpoint inhibition response Principal Investigator: Dr Laura Randle, University of Liverpool PhD Studentship
Development and disease modelling in engineered vascular tissues Principal Investigator: Professor Manuel Mayr, Imperial College London PhD Studentship
An iPSC based xeno-free platform to assess the foreign body response against new biomaterials Principal Investigator: Professor Amir Ghaemmaghami, University of Nottingham Project grant
Developing patient-derived organoids to dissect the cellular & molecular mechanisms underpinning resolving and persistent forms of arthrofibrosis Principal Investigator: Professor Stephanie Dakin, University of Oxford Project grant
A microfluidic human 'pelvis-on-a-chip' model to study ascending urinary tract infection Principal Investigator: Professor Jennifer Rohn, University College London PhD Studentship
Identification of the molecular and cellular mechanisms driving cardiac fibrosis: A novel ex vivo approach to target identification and validation Principal Investigator: Dr Lee Borthwick, Newcastle University PhD Studentship
Development of a fully humanised model for understanding platelet function Principal Investigator: Dr Alice Pollitt, University of Reading Project grant
Replacing sentinel animals with environmental health monitoring Current contact: Dr Khia Dobbinson, Office-led project
A human 3D bone-sensory nerve co-culture model to investigate bone-derived pain Principal Investigator: Professor Deborah Mason, Cardiff University Project grant
Could ultrasonic vocalisations provide the elusive, graded measure of affective state needed to inform refinements For The Laboratory Rat? Principal Investigator: Professor Emma Robinson, University of Bristol Project grant
Developing bovine immune organoids for the screening of vaccine candidates Principal Investigator: Dr Rachel Tanner, University of Oxford Project grant
Cell based assay for tetanus vaccine and antitoxin production Principal Investigator: Professor Andrew Peden, University of Sheffield Project grant
Review of the value of urinalysis assessments in toxicity studies Current contact: Dr Fiona Sewell, Office-led project
Review of the use of two species in regulatory toxicology studies: Phase II - molecules following ICH M3(R2) Current contact: Fiona Sewell, Office-led project
Establishment of the thermotolerant Arabian killifish as a model for infection studies Principal Investigator: Dr Tetsuhiro Kudoh, University of Exeter Project grant
A high-throughput spheroid fusion platform for the templated-assembly of 3D neuromuscular junctions Principal Investigator: Dr Fabrice Gielen, University of Exeter Grants
Human organoid model to generate mucosal immune cell populations Principal Investigator: Dr Joana Neves, King's College London Grants