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Impact stories

631 results

A computational framework to investigate the mechanical role of the extracellular matrix in tissue development and disease

Principal Investigator: Dr Nargess Khalilgharibi, University College London

Fellowship

Myocardial slices to study cardiovascular disease in vitro

Principal Investigator: Professor Cesare Terracciano, Imperial College London

Project grant

A next generation Quiescence and Cell Cycle Indicator for the refinement and reduction of animal usage in proliferation assays

Principal Investigator: Dr Richard Mort, Lancaster University

PhD Studentship

Dr Richard Mort with colleagues by a low wall with trees in the background

A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders

Principal Investigator: Dr Rhiannon Morgan, University of Liverpool

Fellowship

Modelling O-GlcNAc transferase intellectual disability syndrome in Drosophila

Principal Investigator: Professor Daan van Aalten, University of Dundee

PhD Studentship

Engineering Galleria Mellonella as a model for infection, immunity and inflammation

Principal Investigator: Dr James Wakefield, University of Exeter

Project grant

CleanCut: Developing a human in vitro model to assess the safety of gene edited human haemopoietic stem cells

Contractor: Dr Alessandro Rotilio, MOAB srl

CRACK IT Challenge

A novel Drosophila platform to replace the use of mice and zebrafish for the study of ER-mitochondria interactions

Principal Investigator: Dr Alessio Vagnoni, King's College London

Skills and Knowledge Transfer grant

Developing a chick embryo model to aid in development of personalised therapies for malignant pleural mesothelioma

Principal Investigator: Professor Judy Coulson, University of Liverpool

Project grant

Do male mice prefer to live on their own?

Principal Investigator: Professor Emma Robinson, University of Bristol

Project grant

Focused molecular understanding of hypertrophic cardiomyopathy using CRISPR-engineered human pluripotent stem cell-derived cardiomyocytes

Principal Investigator: Dr Diogo Mosqueira, University of Nottingham

Fellowship

Development of an invertebrate model of alternating hemiplegia of childhood

Principal Investigator: Dr Steven Clapcote, University of Leeds

PhD Studentship

Fasting-induced torpor in mice: effects on sleep and behaviour

Principal Investigator: Professor Vladyslav Vyazovskiy, University of Oxford

PhD Studentship

Development and characterization of a novel endothelialized in vitro model of human atherothrombosis

Principal Investigator: Dr Sarah Jones, Manchester Metropolitan University

PhD Studentship

An organotypic model of the bone remodelling process

Principal Investigator: Dr Amy Naylor, University of Birmingham

PhD Studentship

A 3Rs approach to tumour metastasis: investigating the role of cancer stem cells in metastasis using an in vitro microfluidic model

Principal Investigator: Dr Adrian Biddle, Queen Mary University of London

PhD Studentship

Modelling Candida albicans infection of the human gut using human intestinal organoid cultures

Principal Investigator: Dr Silvia Gratz, University of Aberdeen

PhD Studentship

Refining weaning age in macaques destined for neuroscience research

Principal Investigator: Professor Melissa Bateson, Newcastle University

PhD Studentship

Maternal immune activation: advancing from rodents to humans through a development of a hIPSC model to study gene x environment interactions

Principal Investigator: Dr Anthony Vernon, King's College London

PhD Studentship

Development of novel models of kidney damage using induced human pluripotent stem cells

Principal Investigator: Dr Derek Brazil, Queen's University Belfast

PhD Studentship