An integrated platform to assay melanoblast and melanoma invasion of epidermis in vitro Principal Investigator: Dr Richard Mort, University of Edinburgh PhD Studentship
Structural identifiability and indistinguishability analysis as tools for quantitative and systems pharmacology to support the 3Rs Principal Investigator: Dr Michael Chappell, University of Warwick Strategic grant
Human pluripotent stem cell cardiomyocytes and hepatocytes with engineered genotypes for drug safety evaluation Principal Investigator: Professor Chris Denning, University of Nottingham Project grant
Validating reward-related behaviour for welfare assessment, and improving welfare through increased predictability of events Principal Investigator: Professor Hannah Buchanan-Smith, University of Stirling Project grant
State of the art in vitro models which accurately predict human liver toxicity Contractor: Dr Dave Hay, CRACK IT Solution
Establishment of consensual husbandry protocols for laboratory Xenopus laevis using novel physiological and behavioural techniques Principal Investigator: Dr Charlotte Hosie, University of Chester Project grant
Prediction of human cardiotoxic QT prolongation using in vitro multiple ion channel data and mathematical models of cardiac myocytes Principal Investigator: Dr Gary Mirams, University of Oxford Strategic grant
A new sensor platform combining plastic antibodies with simple thermal detection Contractor: Dr Marloes Peeters, CRACK IT Solution
Developing an in vitro approach to study transmission of respiratory viruses Principal Investigator: Professor Wendy Barclay, Imperial College London Project grant
Individually customisable, non-invasive head immobilisation for primates with the option for voluntary engagement Principal Investigator: Professor Christopher Petkov, Newcastle University Pilot study grant
Development and validation of an automated test of animal affect and welfare for laboratory rodents Principal Investigator: Professor Michael Mendl, University of Bristol Project grant
Use of PrP transgenic Drosophila to measure mammalian prion infectivity Principal Investigator: Dr Raymond Bujdoso, University of Cambridge Project grant
eGUT: a Tool for Predictive Computer Simulation of the Gut Microbiota and Host Interactions Principal Investigator: Dr Jan-Ulrich Kreft, University of Birmingham Project grant
Improving the principles of the 3Rs through new integrative metabolomic and gene expression resources for signalling studies in burn injuries Principal Investigator: Dr Istvan Nagy, Imperial College London PhD Studentship
Refining the study of fatigue in mouse models of chronic liver disease Principal Investigator: Dr Claire Richardson, Newcastle University Fellowship
CRANNME: The complete removal of animal use for neuromuscular effectors testing Principal Investigator: Professor Mark Lewis, Loughborough University Pilot study grant
Non-invasive imaging to reduce and refine the use of animals and monitor their welfare during the course of experimentations in oncology Principal Investigator: Dr Francois Lassailly, Cancer Research UK Pilot study grant
In vitro methods for replacement of current in vivo assays for development of drugs against heterogeneous cancer stem cell populations Principal Investigator: Dr Adrian Biddle, Queen Mary University of London Fellowship
The role of bronchoconstriction in the development of airway remodelling and its effects upon lung function Principal Investigator: Dr Amanda Tatler, University of Nottingham Fellowship
Investigation of behavioural and physiological responses to fin-clipping in zebrafish Principal Investigator: Ms Gidona Goodman, University of Edinburgh Pilot study grant