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Guidance document on opportunities to reduce and refine the use of GA mice through cryopreservation and sharing.

Reducing and refining acute toxicity tests in the pharmaceutical and chemicals industries.

Providing an evidence base to refine and reduce the use of vertebrates in (regulatory) ecotoxicology studies

Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies

Supporting the uptake of new approach methodologies to reduce reliance on traditional animal toxicity tests

Guidance on reducing or refining animal use for studies with cardiovascular, central nervous system and respiratory functional measurements.

Projects providing guidance to reduce animal use or refine procedures within toxicology studies.

A webinar series from a cross-European group of 3Rs centres exploring the challenges and opportunities of replacing BMEs.

Information to help refine the housing and husbandry of the laboratory hamster.

Information to help refine the housing and husbandry of the laboratory mouse.

Details of the Mouse Grimace Scale, including a poster for display in laboratory rooms and corridors.

Details of the Rat Grimace Scale, including a poster for display in laboratory rooms and corridors.

Information to help refine the housing and husbandry of the laboratory dog.

Tips to avoid common pitfalls when describing your experimental design and methodology in a funding proposal.

A dedicated, open access portal for our Grant holders to showcase their 3Rs research.

An introduction to systematic reviews, a powerful method used to assess accumulating evidence related to a specific research question.

Reasons for conducting a pilot study and what you can do with the results.