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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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31 results

Guiding strategy and encouraging the adoption of microsampling techniques within any research or safety study.

A brown and white rat in the gloved hands of an animal technician.

Guidance on reducing or refining animal use for studies with cardiovascular, central nervous system and respiratory functional measurements.

A beagle at an indoor play area

Techniques for blood sampling in laboratory animal species to ensure the most appropriate technique is chosen.

Five needles with empty syringes on a pale blue background

Approaches for sampling blood in the marmoset, covering non-surgical and terminal techniques.

Two marmosets in an outdoor enclosure, with an icon of a needle and syringe on a yellow background in the corner of the image.

How magnetic resonance imaging (MRI) is contributing to the 3Rs in neuroscience studies involving non-human primates.

A macaque looking to its left
External link

A dedicated website with resources for everyone who works with, or is interested in, laboratory macaques.

A macaque eating

Learn more about why the single use of needles should be standard practice and how to implement this in your facility.

A rat being injected with a hypodermic needle
External link

How to recognise and prevent pain, suffering and distress in laboratory animals.

A screenshot of an e-learning module activity, with a photo of a white rat labelled with green "i" buttons to indicate where trainees can click for more information. A label reads "Body posture: the posture is normal".
External link

Principles and techniques for humane killing of laboratory animals.

Mice in a cage with a pipe connected to it, to be used for euthanasia.
External link

Post-operative pain relief for laboratory animals, including selecting and using analgesics.

A close up of an animal being injected with analgesia
External link

Recognising pain and assessing its severity in laboratory animals following surgery.

Screenshot of the EU 21-8 training module, featuring a mouse on a gloved hand