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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

Search our 3Rs resource library

Use the filters below to narrow down our resources to those relevant to your role, the model you are interested in, or by topic area. Filters are best used by combining two or more to narrow down the results.

233 results

Projects to ensure that the in vivo tests involved in ED assessment are as robust as possible, particularly focusing on aquatic species.

Zebra fishes in tank

Our self-assessment tools are currently under redevelopment. Find out more about this project and our future plans.

Icon of a checklist with "3Rs" enlarged by a magnifying glass

Bringing researchers together to exchange information, support collaborations and share technologies to maximise 3Rs impacts in oncology research.

A graphic showing a network of circles, the three in the centre feature icons depicting cancer cells, chemotherapy drugs and DNA

NC3Rs resources for oncology researchers developing 3Rs models or establishing new collaborations.

A cell culture plate containing pink liquid under a microscope. A gloved hand is holding the plate while another is pipetting liquid into it.

Resources to help researchers initiate collaborations and share technologies to maximise the scientific and 3Rs impact of oncology models.

Decorative image

Guidance, information and recommendations for those working with zebrafish.

Zebrafish swimming in a tank.

Learn more about what NAMs are and how they can be applied to progress the 3Rs.

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Resources to help researchers initiate collaborations and share technologies to maximise the 3Rs impact of cardiovascular models.

Cardiovascular network plastic heart on textbook

Bringing researchers together to exchange information, support collaborations and share technologies to maximise 3Rs impacts.

Graphic showing an anotomical heart, blood cells and ECG readout.

NC3Rs resources for cardiovascular researchers developing 3Rs models or establishing new collaborations.

Organ on a chip microphysiological system

Practical advice on calculating how many matings to set up, including available breeding calculator tools.

A mouse illustration with maths symbols and numbers

A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.

White icons of a magnifying glass focused on a mouse, on a blue background

Guidance on the role of the 3Rs Champion within the research community.

A white trophy with the term '3Rs' on it sits on a bright yellow background.