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Our Project grant scheme is open for applications, supporting the development of new 3Rs approaches and technologies!

NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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Use the filters below to narrow down our resources to those relevant to your role, the model you are interested in, or by topic area. Filters are best used by combining two or more to narrow down the results.

16 results

Guidance on best practices in confirming, archiving and maintaining strains, as well as re-establishing colonies after a pause.

A litter of black mice with an adult mouse, nesting in the corner of their home cage

Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.

A white sperm and egg icon on a blue background

A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.

White icons of a magnifying glass focused on a mouse, on a blue background

F0-ols Rush In: Improving reproducibility and avoiding genetic mosaicism using CRISPR/Cas9 technology.

A white icon of the DNA double helix on a purple background.