Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
We have committed over £1M towards the development of non-animal methods.
We look back at 20 years of innovation in the 3Rs in an AI special issue of The Biologist, the magazine from the Royal Society of Biology.
21 awards have been supported with DSIT funding to accelerate the uptake of non-animal approaches and replace animal-derived products in research and testing.
Hear how lecturers at the University of Nottingham are using the Experimental Design Assistant (EDA) as an engaging and practical way to teach experimental design.
The ARRIVE study plan is a freely available resource to assess the rigour and improve the transparency of planned animal research.
£10M will be available to support interdisciplinary research clusters.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
