Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
OECD to develop new guidance to minimise fish use in some studies, based on NC3Rs-led work.
£15.9M awarded to develop human in vitro models of complex disease.
Non-invasive, continuous monitoring of rodent behaviour improves both animal welfare and scientific accuracy in safety pharmacology.
A national training initiative in France is using the EDA to embed robust experimental design into real-world research practice.
NC3Rs staff have co-authored a new chapter in the IACUC Handbook to support ethical review bodies in assessing the reliability of animal research.
Report highlights the outcomes of the first UK funding call for infrastructure to support animal replacement methods, delivered by the NC3Rs.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
