We are the main funder of 3Rs research in the UK with over £58 million committed since 2004. We have a range of schemes to support projects, infrastructure, and training and career development.

The science we fund delivers 3Rs benefits in addition to providing knowledge which helps to improve understanding of human diseases, develop efficacious and safe medicines, and protect the environment.

We also fund the commercialisation of 3Rs technologies through our CRACK IT programme.

Open calls

These awards support NC3Rs-funded researchers past and present to engage with the public. The funding is available as an open rolling call.
Details of all of our 3Rs funding schemes from project grants to PhD studentships.
Information and guidance on the application process for each of our schemes (opens a PDF document).
All invited full applications must be submitted via the RCUK joint electronic submission system (Je-S).
Guidance for clearly conveying the potential 3Rs impact of proposed research.
A presentation containing top tips for applicants from our funding team.
Responsibilities of award holders.
Post-award information including Panel outcome reports and award success rates.
Learn about areas of strategic importance highlighted across our funding schemes.