The book was coedited by Dr David Allen, from Integrated Laboratory Systems in North Carolina. Dr Allen has many years of experience in evaluating alternative toxicology methods.
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Just as mice and rats are not humans, a mathematical model is not a human, but, like mice and rats, a model can be thought to be representative of human response to chemical exposure.
The aim of the CRACK IT Challenges open innovation platform – to connect scientists from different backgrounds in order to solve scientific and business problems with a 3Rs theme – closely aligns with our mission at Edinburgh BioQuarter, to stimulate
Professor Dr. Thomas Korff from the Institute of Physiology and Pathophysiology, University of Heidelberg has recently been credited by the German Research Foundation (DGF) for his outstanding work in improving animal welfare in scientific research.
Translations of our ARRIVE reporting guidelines are now available in Italian and Portuguese.
The funding will support five projects to increase the utility of a broad spectrum of imaging techniques, including bioluminescence, radio labelling and implantable technology.
Dr Caroline Brennan, from Queen Mary University of London, tells the NC3Rs the top five reasons why zebrafish are her model of choice.
Re-evaluating animal models of pain could minimise animal use, improve the quality of scientific experiments and accelerate the development of novel pain treatments, the authors of a recent paper urge.
NC3Rs funded post-doctoral researcher Dr Maria Vinci, from The Institute of Cancer Research, London, tells us how she became interested in communicating her research to a wider audience and the impact this has had.
Infectious microbes are responsible for one in every three deaths worldwide, killing a staggering 14 million people each year.
Dr Daniel Adams speaks to the NC3Rs about how he drew on techniques from modern orthopaedics and dentistry to develop the refined recording chamber.
A popular UK training resource to support the adoption of best practice for commonly used laboratory procedures in animal research is now available in Chinese.
The expert panel judging entries to this year’s NC3Rs 3Rs Prize selected Dr Fejer’s work for commendation because of the positive step his research can make towards reducing animal use in the study of infection and immunity.
NC3Rs-funded researchers will now be able to apply for additional funds to support activities which engage the public with their 3Rs research.
Using the new method, cells from one mouse could be used to test 1000 drug compounds to treat liver disease, and reduce animal use by up to 50,000.
Research that has for the first time successfully grown "mini-livers" from adult mouse stem cells has won the UK's international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of
A 50 per cent reduction in fish using the three-spined stickleback to test for harmful effects of chemicals. An endocrine disruptor is a term given to chemicals that, when absorbed into the body, either mimic or block hormones.
Dr Vicky Robinson, Chief Executive, NC3Rs, said: "I welcome the Coalition Government's new plan to work to reduce the use of animals in research.
Seventeen R&D consortia have been awarded up to £100,000 each in a bid to solve five of the pharmaceutical industry's biggest drug discovery and development challenges, where the replacement, reduction and refinement of animals in research (the 3Rs)
Research could improve the welfare of millions of fish used by scientists around the world.
