In vitro, off-host, rearing of the poultry red mite to supply parasites for development of new control methods
Principal Investigator:
Dr Alasdair Nisbet
Institution:
- Moredun Research Institute
- Project grant
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Cryo-storing research lines of chicken to eliminate breeding and save genetic resources
Principal Investigator:
Dr Michael McGrew
Institution:
- University of Edinburgh
- Project grant
Using ex vivo organotypic cultures to investigate donor cell integration in the gut
Principal Investigator:
Dr Conor McCann
Institution:
- University College London
- Project grant
A Drosophila single-cell resource for brain metabolism research
Principal Investigator:
Dr Alex Gould
Institution:
- The Francis Crick Institute
- Project grant
Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research
Principal Investigator:
Dr Manolis Fanto
Institution:
- King's College London
- Project grant
Developing stem cell-derived macrophages to study host pathogen interactions and advance strategies to combat globally important disease in the pig
Principal Investigator:
Dr Thomas Burdon
Institution:
- University of Edinburgh
- Project grant
Using a novel, high welfare in vivo feeding device for poultry red mite and its integration with other novel tools for this parasite
Principal Investigator:
Dr Alasdair Nisbet
Institution:
- Moredun Research Institute
- Skills and Knowledge Transfer grant
Sharing new non-invasive circadian phenotyping methods
Principal Investigator:
Professor Stuart Peirson
Institution:
- University of Oxford
- Skills and Knowledge Transfer grant
Naturally sterile hybrid mice for the production of embryo transfer recipients
Principal Investigator:
Dr Ben Davies
Institution:
- University of Oxford
- Skills and Knowledge Transfer grant
Establishment of novel macrophage cell lines to study the pathogenesis of respiratory bacterial pathogens in lung alveolar macrophages
Principal Investigator:
Dr Gyorgy Fejer
Institution:
- University of Plymouth
- Skills and Knowledge Transfer grant
WaterR: A tool for better management and monitoring of rodent fluid intake
Principal Investigator:
Dr Paul Dodson
Institution:
- University of Bristol
- Skills and Knowledge Transfer grant
Sharp and to the Point: Developing a device for injections in mice that avoids the re-use of needles
Contractor:
Mr Ian Quirk, Active Needle Technology Ltd
- CRACK IT Challenge
MacuSIM: A microfluidic, in vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials
Principal Investigator:
Dr Savannah Lynn
Institution:
- University of Southampton
- Fellowship
A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders
Principal Investigator:
Dr Rhiannon Morgan
Institution:
- University of Liverpool
- Fellowship
Modelling radiobiology effects of X-rays in small laboratory animals to develop guidelines for preclinical computed tomography imaging
Principal Investigator:
Dr Wendy McDougald
Institution:
- University of Edinburgh
- Fellowship
A computational framework to investigate the mechanical role of the extracellular matrix in tissue development and disease
Principal Investigator:
Dr Nargess Khalilgharibi
Institution:
- University College London
- Fellowship
Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity
Principal Investigator:
Dr Grant Wheeler
Institution:
- University of East Anglia
- PhD Studentship
Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias
Principal Investigator:
Dr Katja Gehmlich
Institution:
- University of Birmingham
- PhD Studentship
INDUCE-seq: a novel tool for next generation risk assessment
Principal Investigator:
Professor Simon Reed
Institution:
- Cardiff University
- PhD Studentship
Developing an in silico, spectroscopic imaging toolkit for assessing skin penetration
Principal Investigator:
Dr Tao Chen
Institution:
- University of Surrey
- PhD Studentship
An improved C. elegans model of Alzheimer's disease to monitor neuronal signalling activity
Principal Investigator:
Dr Patricija van Oosten-Hawle
Institution:
- University of Leeds
- PhD Studentship
Modelling O-GlcNAc transferase intellectual disability syndrome in Drosophila
Principal Investigator:
Professor Daan van Aalten
Institution:
- University of Dundee
- PhD Studentship
A 3Rs approach to assess drug toxicity on the mammalian embryo during early pregnancy in vitro
Principal Investigator:
Dr David Turner
Institution:
- University of Liverpool
- PhD Studentship
Direct replacement of secondary antibodies by Affimer proteins
Principal Investigator:
Dr Christian Tiede
Institution:
- University of Leeds
- PhD Studentship
A next generation Quiescence and Cell Cycle Indicator for the refinement and reduction of animal usage in proliferation assays
Principal Investigator:
Dr Richard Mort
Institution:
- Lancaster University
- PhD Studentship