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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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65 results

Guidance, information and recommendations for those working with zebrafish.


Guidance on implementing positive reinforcement training methods.

Marmoset being handfed as part of positive reinforcement training

Guidance on non-aversive methods for handling mice. Includes tutorials, FAQs and tips for implementation.

Three black mice, one of them is being handled with a clear plastic tunnel

Guidance on best practices in confirming, archiving and maintaining strains, as well as re-establishing colonies after a pause.

A litter of black mice with an adult mouse, nesting in the corner of their home cage