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International 3Rs Prize now open for applications. £30k prize (£2k personal award) for outstanding science with demonstrable 3Rs impacts.

NC3Rs | 20 Years: Pioneering Better Science

Search our 3Rs resource library

Use the filters below to narrow down our resources to those relevant to your role, the model you are interested in, or by topic area. Filters are best used by combining two or more to narrow down the results.

72 results

How funding bodies can embed the 3Rs in their peer review process, including details of our review and advice service.

Icon representing peer review: two people connected by arrows going round a paper

A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.

White icons of a magnifying glass focused on a mouse, on a blue background

Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.

A white sperm and egg icon on a blue background

Key issues for the humane killing of laboratory animals.

A laboratory technician and a rat in a tank

Practical advice on calculating how many matings to set up, including available breeding calculator tools.

A mouse illustration with maths symbols and numbers

Professor Jane Hurst and Mr John Waters answer your questions about the refined handling techniques.

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Information and resources on malocclusion in mice to improve welfare within a research setting.

One mouse exhibiting healthy teeth and another exhibiting unhealthy, maloccluded teeth

The positive impact playpens have on laboratory rat welfare, and guidance on how to set one up in your institution.

A tall cage which has been used to create a rat playpen. There are three different tiers with ladders to allow the rats to climb up between each one. A number of white rats can be seen moving between the different levels. Enrichment and play objects are available on each level including an cardboard box that used to hold laboratory gloves, coloured balls, tubes, a wheel and a raised platform on the top level with some bedding material.