Find out about the work we have funded to build the evidence base for refining the use of fish in research.

Find out about the work we have funded to build the evidence base for refining the use of fish in research.
Opportunities for the wider adoption of 3Rs approaches within WHO guidance documents for the quality, safety and efficacy of vaccines and biological therapeutics.
Showcasing our grant holders and how NC3Rs-funded research comes together to develop innovative new 3Rs tools and technologies that are pioneering better science.
To mark eight years since we launched the EDA we have added new functionality making the programme easier to use.
Find out about the £3M the NC3Rs has invested to replace, reduce or refine the use of animals in research to better understand and treat Alzheimer’s disease.
The latest funding from the NC3Rs focuses on applying the 3Rs across a variety of fields from laboratory rat welfare to vaccine production for humans and cattle.
As Chair, Professor Julia Buckingham will help to deliver our strategy, prepare for the next core funding bid and promote the UK’s position at the forefront of 3Rs research and development.
Exploring the value of engagement and a helpful how-to guide for effective communication.
Discover NC3Rs-funded science to replace animals in research to understand and treat stroke.
Four new Challenges have been announced in this year’s open innovation funding competition.
An animal-free organoid model has won the 3Rs Prize, awarded by the NC3Rs and co-funded by GSK.
An overview of rodent behavioural monitoring including key initiatives that have supported the adoption of these tools and championed the 3Rs.
Registered reports involve peer review prior to data collection to reduce bias and build confidence in studies. This blog showcases the first to be published on the NC3Rs Gateway.
This new and freely available tool will streamline manuscript checks to ensure that animal research is transparently reported in line with ARRIVE Essential 10.
The NC3Rs is seeking a well-connected and ambitious Board Chair to help steer its work over the next three years.
Two new grants to support collaborative projects to identify and validate potential new therapeutic targets.
Our first Mega-CRACK IT Challenge which seeks to exploit advances in computational approaches and machine learning to develop a “Virtual Dog” to ultimately replace their use for chronic toxicity studies.
Independent report assesses the 3Rs landscape and makes recommendations to support implementation across the academic community.
As part of our Technologies to Tools programme, MTI will apply their functional genomics expertise to translate NC3Rs-funded cell-based disease models into industry-ready products and services.
Our top ten announcements and outputs from this year including 100 Tox Team papers published, 150 Project Grant Scheme awards and over £50M committed to replacement projects.