Join our community of researchers, developers, industry and regulatory end-users working together to accelerate the use of new approach methodologies.

Join our community of researchers, developers, industry and regulatory end-users working together to accelerate the use of new approach methodologies.
Common misconceptions around sex-inclusive research, the SIRF framework and how it can be used by scientists, ethical review bodies and funders.
Supporting the uptake of new approach methodologies to reduce reliance on traditional animal toxicity tests
Resources to assist funders in assessing whether animal research conducted overseas conforms to UK welfare standards.
A webinar exploring how optimising housing and handling can improve both zebrafish welfare and data quality.
Winning and highly commended researchers share their work to strengthen the evidence base for replacement technologies at the 3Rs Prize ceremony.
Guidance on choosing the appropriate anesthesia for laboratory animals, including links to further resources.
Quarterly e-newsletter to keep the scientific community updated on news from the NC3Rs Toxicology and Regulatory Sciences programme.
A webinar series from The Togeth3R Consortium of European 3Rs centres showcasing non-animal methods.
An overview of our toxicology and regulatory sciences programme.
Report from an in-person workshop for the Named Information Officer community held in September 2024.
Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies
A joint webinar from the NC3Rs/RSPCA Animals in Science department on refining the use of amphibians in research.
Helping those who work with animals in research to be more effective in searching for and keeping up with information relevant to animal research
Learn more about skin swabbing as a welfare refinement, and how to establish a protocol for skin swabbing in your laboratory.
Learn about the winning in vitro method for evaluating hormone potency and the highly commended organ-on-a-chip device to determine liver toxicity.
Research published on tunnel handling and cupping methods for handling mice
Results from a survey of the Named Information Officer community in the UK, collected and published in 2024.
Support to communicate research to replace, reduce or refine the use of animals.
Our self-assessment tools are currently under redevelopment. Find out more about this project and our future plans.
Exercises to enhance critical analysis skills and improve your ability to evaluate scientific literature.
Guidance and resources to help researchers address the 3Rs in animal licence applications. Focused on the UK but applicable worldwide.
A framework to improve the lives of laboratory rodents through refined management approaches.
Information to help refine the housing and husbandry of the laboratory mouse.