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A framework to improve the lives of laboratory rodents through refined management approaches.
96 results
Guidance, information and recommendations for those working with zebrafish.
Recommendations for reducing aggression between group-housed male mice.
Practical advice on calculating how many matings to set up, including available breeding calculator tools.
Guidance on best practices in confirming, archiving and maintaining strains.
A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.
Answers to some of the most often asked questions on breeding and maintaining GA mouse colonies.
Information on techniques for sampling blood in the mouse, covering non-surgical, surgical and terminal techniques.
Recommendations and guidance from an NC3Rs working group on high-yield rodent behavioural experiments focusing on fluid control and head fixation in
Information and guidance for the use of automated systems to monitoring the behaviour of animals in preclinical research.
Webinar on the pioneering approach to implementing refinements for handling mice and rats by Research Institutes of Sweden (RISE).
A webinar providing an overview of the Precision Injection System developed to address the 2019 Sharp and to the Point Challenge.
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A series of video tutorials to develop skills in the administration of substances and apply best practice in aseptic surgical techniques in rodents.
Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.
Supporting technicians in assessing the welfare impact of enrichment.
Guidance on modifying our example protocols to design your own studies.
Guidance on using motivation tests to evaluate environmental enrichment.
Guidance on using ethograms to evaluate environmental enrichment, including examples.
Guidance on using preference tests to evaluate environmental enrichment.
Guidance on how to conduct an evaluation of environmental enrichment.
Posters and other resources on the use of grimace scales to assess pain in laboratory animals.
Details of the Rabbit Grimace Scale, including a poster for display in laboratory rooms and corridors.
Techniques for blood sampling in laboratory animal species to ensure the most appropriate technique is chosen.
Information on techniques for sampling blood in the rat, covering non-surgical, surgical and terminal techniques.
