Dr Simon Bate, from Statistical Sciences, GSK, covers a few questions about statistics and the 3Rs that he regularly encounters.
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Discussing key considerations when determining the effect size for a study, including why this is important for sample size calculations.
A recorded talk explaining the dangers of underpowered experiments and how good design can increase the chances of finding reliable results.
A video overview of common practices in preclinical research, and specific actions that can be taken to improve its robustness.
A recorded talk highlighting where bias can be introduced into experiments and the implications for results.
Videos from our May 2018 workshop on experimental design for panel members of the NC3Rs, BBSRC, CRUK, MRC and Wellcome Trust.
Professor Jane Hurst of the University of Liverpool shares the evidence base supporting refined mouse handling techniques as well as practical advice
Group housed zebrafish show lower levels of stress and anxiety when they undergo procedures than those who are housed singly.
Guidelines on non-human primate accommodation, care and use adopted by the major UK bioscience funders.
Download short video clips for use in in-house training.
Key issues for the humane killing of laboratory animals.
Resources to help researchers access and use human tissue.
Seven related principles that all research institutions should adopt or consider.
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A comprehensive resource on common marmosets, funded by the NC3Rs.
It starts at the very beginning: Scientific and welfare reasons for reviewing neonate care
General principles in analgesia to support best practice.
Advice on rehoming ex-laboratory non-human primates.
Things to consider when designing your animal experiments.
F0-ols Rush In: Improving reproducibility and avoiding genetic mosaicism using CRISPR/Cas9 technology.
Examples of study designs that may be used for microsampling from either main study animals or from satellite groups of animals.
A discussion on the possible impact of genetic drift on the integrity of the data from GA mouse studies
Watch your Back! The importance of background strain.
Primate sensory capabilities and communication signals: implications for care and use in the laboratory
A discussion of the animal welfare challenges around the generation of GA mice, and strategies for improving welfare.
