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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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Keep up to date with the latest news from the NC3Rs, including the researchers we fund. Follow us on social media and subscribe to our newsletter to get the latest updates directly.

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Over 3,000 members of the public took part in NC3Rs events and activities last year to learn about the 3Rs.

A scientist giving a demonstration at a primary school.

Hear how lecturers at the University of Nottingham are using the Experimental Design Assistant (EDA) as an engaging and practical way to teach experimental design.

Early career researchers at a workshop on experimental design.

Our Experimental Design Assistant (EDA) helps you to design robust and meaningful animal experiments. With a wealth of information, features and tools, here are our tips to help you make the most of the EDA.

A diagram showing how the EDA can be used to represent a two group comparison experiment. The EDA works by dragging and dropping 'nodes' which appear as coloured shapes. These are then connected with arrows or ‘links’ showing how different parts of an experiment relate to each other. The EDA then uses computer-based logical reasoning to provide feedback on the experimental design.

NC3Rs Programme Manager Dr Elliot Lilley reflects on the united vision that drove the success of our project to embed the 3Rs in quality, safety and efficacy testing of vaccines and biological therapeutics.

Portrait of Dr Elliot Lilley

Hear from the NC3Rs NAMs Advisory Group as they discuss their recent paper on how to overcome the hurdles to embedding new approach methodologies (NAMs) in chemical and drug safety assessment.

Three images representing NAMs: a laboratory flask, an environmental landscape and a computer-designed molecule.

Discover how the NC3Rs works to address the use of dogs in research and replace the use of animals in toxicity testing with non-animal methods, two topics being debated in Parliament later today.

Portrait of Dr Vicky Robinson, Chief Executive, NC3Rs.

2024 marks the 20-year anniversary of the NC3Rs. Discover the celebratory activities we have planned over the course of the year in our latest blog.

20-year anniversary logo. 20 years of pioneering better science

Registered reports involve peer review prior to data collection to reduce bias and build confidence in studies. This blog showcases the first to be published on the NC3Rs Gateway.

F1000Research logo above portraits of Professor Alistair Lawrence and Dr Vincent Bombail, authors of the first Registered Report on the NC3Rs Gateway

We recommend that all NC3Rs grant holders and stakeholders deposit their cells with The European Bank for induced pluripotent Stem Cells (EBiSC).

Stem cells stained and imaged