Bibliography and relevant resources for those working in the field of toxicology and regulatory sciences.
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Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies
Learn more about skin swabbing as a welfare refinement, and how to establish a protocol for skin swabbing in your laboratory.
Projects to ensure that the in vivo tests involved in ED assessment are as robust as possible, particularly focusing on aquatic species.
Guidance and resources to help researchers address the 3Rs in animal licence applications. Focused on the UK but applicable worldwide.
Support to communicate the 3Rs and impacts arising from your research.
A framework to improve the lives of laboratory rodents through refined management approaches.
Information to help refine the housing and husbandry of the laboratory mouse.
Guiding strategy and encouraging the adoption of microsampling techniques within any research or safety study.
Guidance for those overseeing animal research at institutions on recognising 3Rs opportunities and putting them into practice.
Guidance, information and recommendations for those working with zebrafish.
Guidance on best practices in handling and restraint for mice, rats and other laboratory rodents.
Recommendations for reducing aggression between group-housed male mice.
Practical advice on calculating how many matings to set up, including available breeding calculator tools.
A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.
Answers to some of the most often asked questions on breeding and maintaining GA mouse colonies.
Guidance on the role of the 3Rs Champion within the research community.
Information on techniques for sampling blood in the mouse, covering non-surgical, surgical and terminal techniques.
A set of resources to support the adoption of the 3Rs in quality control and batch release testing of vaccines and biological therapeutics
Reasons for conducting a pilot study and what you can do with the results.
Checklists to assist funders in assessing whether animal research conducted overseas conforms to UK welfare standards.
How funding bodies can embed the 3Rs in their peer review process, including details of our review and advice service.
Recommendations and guidance from an NC3Rs working group on high-yield rodent behavioural experiments focusing on fluid control and head fixation in
Information and guidance for the use of automated systems to monitoring the behaviour of animals in preclinical research.
